Synlett

Tandem Meinwald rearrangement-Fischer indolisation: a one-pot conversion of epoxides into indoles

JR Donald, RJK Taylor

Index: Donald, James R.; Taylor, Richard J. K. Synlett, 2009 , # 1 p. 59 - 62

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Citation Number: 9

Abstract

Abstract A tandem Sc (OTf) 3-mediated Meinwald epoxide rearrangement-Fischer indole synthesis is reported. Optimisation and scope and limitation studies are described. In addition, preliminary investigations to develop a telescoped epoxidation-Meinwald rearrangement-Fischer indole sequence are outlined.

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