The Journal of Organic Chemistry

Synthesis of the Streptomyces ambofaciens antineoplastic constituent 6-diazo-5-oxo-L-norleucine

GR Pettit, PS Nelson

Index: Pettit, George R.; Nelson, Paul S. Journal of Organic Chemistry, 1983 , vol. 48, # 5 p. 741 - 744

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Citation Number: 9

Abstract

(5) Cf. HA DeWald and AM Moore, J. Am. Chem. Soc., 80, 3941 (1958); F. Weygand, H. Bestmand, and E. Klieger, Chem. Ber., 91, 1037 (1968). The latter report is closely related to our study and was located (during a search of diazo ketone rearrangement reactions) when the present contribution was in press. Apparently the Weygand synthesis was missed in prior summaries of DON a theses and abstracts.(6) DON is moat stable at pH 4.5-6.5 F ...