The Journal of Organic Chemistry

Syntheses of. beta.-diamines and. beta.-amino alcohols from. alpha.,. beta.-unsaturated ketones and aldehyde, methylamine, and borohydride reducing agents

MG Andrews, JA Mosbo

Index: Andrews,M.G.; Mosbo,J.A. Journal of Organic Chemistry, 1977 , vol. 42, p. 650 - 652

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Citation Number: 11

Abstract

I\ Iii thylamine was likely the first step followed by reduction of one or more of the carbonyl- imine equilibrium species. This mechanism is consistent with the experimental results.(Although imines are depicted above as being the species reduced to amines by both reagents, Borch, Bernstein, and Durst have reported that iminium ions are the actual species reduced by sodium cyanoborohydride.”)