Organic & biomolecular chemistry

Fluorescent organic nanoparticle formation in lysosomes for cancer cell recognition

HH Lin, SY Su, CC Chang

Index: Lin, Hsin-Hung; Su, Sheng-Yuan; Chang, Cheng-Chung Organic and Biomolecular Chemistry, 2009 , vol. 7, # 10 p. 2036 - 2039

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Citation Number: 35

Abstract

We present a convenient method to prepare fluorophores 3-or 3, 7-divinyl substituted 10H- phenothiazines and their protonation forms can aggregate to become fluorescent organic nanoparticles (FONs) with bright fluorescent spots in the lysosomes of cancer cells but not normal cells.