(3S,5R,E)-甲基 7-(3-(4-氟苯基)-1-异丙基-1H-吲哚-2-基)-3,5-二羟基庚-6-烯酸酯

• 常用名: (3S,5R,E)-甲基 7-(3-(4-氟苯基)-1-异丙基-1H-吲哚-2-基)-3,5-二羟基庚-6-烯酸酯
• 英文名: Fluvastatin Methyl Ester
• CAS号: 93957-53-0
• 分子量: 425.49300
• 密度: 1.18 g/cm3
• 沸点: 627.5ºC at 760 mmHg
• 分子式: C₂₅H₂₈FNO₄
• 熔点: N/A
• 闪点: 333.3ºC

用途

Fluvastatin Methyl Ester is a precursor for Fluvastatin, which is a blocker of the liver enzyme HMG-CoA reductase.

名称

• 中文名: 氟伐他汀甲酯
• 英文名: Fluvastatin methyl ester
• 中文别名: (3R,5S,6E)-7-[3-(4-氟苯基)-1-(1-甲基乙基)-1-氢-吲哚-2-基]-3,5-二羟基庚-6-烯酸甲酯 | [3R,5S-(E)]-7-[3-(4-氟苯基)-1-异丙基-1H-吲哚-2-基]-3,5-二羟基-6-庚烯酸叔丁酯

物理化学性质

• 密度: 1.18 g/cm3
• 沸点: 627.5ºC at 760 mmHg
• 分子式: C₂₅H₂₈FNO₄
• 分子量: 425.49300
• 闪点: 333.3ºC
• 精确质量: 425.20000
• PSA: 71.69000
• LogP: 4.71650
• InChIKey: BOCZYIUKFAQNLG-DSJWGCTQSA-N
• SMILES: COC(=O)CC(O)CC(O)C=Cc1c(-c2ccc(F)cc2)c2ccccc2n1C(C)C
• 折射率: 1.568
• 储存条件: 2-8℃，密闭，干燥

英文别名

• methyl erythro-(E)-3,5-dihydroxy-7-[3-(4-fluorophenyl)-1-(1-methylethyl)indol-2-yl]hept-6-enoate
• FLUVASTATIN MEHTYL ESTER
• methyl (+/-)-erythro-(E)-7-[3'-(4''-fluorophenyl)-1'-(1''-methylethyl)indole-2'-yl]-3,5-dihydroxyhept-6-enoate
• F4 TERT-BUTYL(E)-3,5-DIHYDROXY-7-[3-(4-FLUOROPHENYL)-1-METHYLETHYL-INDOL-2'-YL] HEPT-6-ENOATE
• methyl (3r,5s,6e)-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1h-indol-2-yl]-3,5-dihydroxy-6-heptenoate
• (3R,5S,6E)-rel-7-[3-(4-Fluorophenyl)-1-(1-Methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic Acid Methyl Ester
• [R*,S*-(E)]-(+/-)-7-[3-(4-Fluorophenyl)-1-(1-Methylethyl) -1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic Acid Methyl Ester
• fluvastatin,methyl ester of
• MFCD08458340