Acetyl-(Tyr1,D-Arg2)-GRF (1-29) amide

• 常用名: Acetyl-(Tyr1,D-Arg2)-GRF (1-29) amide
• 英文名: Acetyl-(Tyr1,D-Arg2)-GRF (1-29) amide
• CAS号: 93942-91-7
• 分子量: 3485.027
• 密度: 1.5±0.1 g/cm3
• 沸点: N/A
• 分子式: C₁₅₄H₂₅₅N₄₇O₄₃S
• 熔点: N/A
• 闪点: N/A

Acetyl-(Tyr1,D-Arg2)-GRF (1-29) amide用途

乙酰-(D-Arg2)-GRF(1-29)酰胺(人)是生长激素释放因子(GRF)的拮抗剂。乙酰-(D-Arg2)-GRF(1-29)酰胺(人)抑制生长激素(GH)的释放,可用于内分泌研究[1]。

Acetyl-(Tyr1,D-Arg2)-GRF (1-29) amide名称

• 英文名: 1-29-Somatoliberin (human pancreatic islet), N-acetyl-2-D-arginine-29-L-argininamide

Acetyl-(Tyr1,D-Arg2)-GRF (1-29) amide生物活性

• 描述: 乙酰-(D-Arg2)-GRF(1-29)酰胺(人)是生长激素释放因子(GRF)的拮抗剂。乙酰-(D-Arg2)-GRF(1-29)酰胺(人)抑制生长激素(GH)的释放,可用于内分泌研究[1]。
• 相关类别:
  研究领域 >> 内分泌
  信号通路 >> 其他 >> 其他
• 靶点:

  Growth hormone releasing factor, GRF; Growth hormone, GH[1]

• 参考文献:

  [1]. Lumpkin MD, et al. Blockade of growth hormone-releasing factor (GRF) activity in the pituitary and hypothalamus of the conscious rat with a peptidic GRF antagonist. Endocrinology. 1989 Mar;124(3):1522-31.

Acetyl-(Tyr1,D-Arg2)-GRF (1-29) amide物理化学性质

• 密度: 1.5±0.1 g/cm3
• 分子式: C₁₅₄H₂₅₅N₄₇O₄₃S
• 分子量: 3485.027
• 精确质量: 3482.893311
• PSA: 1537.18000
• LogP: -5.16
• 折射率: 1.651

Acetyl-(Tyr1,D-Arg2)-GRF (1-29) amide英文别名

• N-Acetyl-L-tyrosyl-D-arginyl-L-α-aspartyl-L-alanyl-L-isoleucyl-L-phenylalanyl-L-threonyl-L-asparaginyl-L-seryl-L-tyrosyl-L-arginyl-L-lysyl-L-valyl-L-leucylglycyl-L-glutaminyl-L-leucyl-L-seryl-L-al anyl-L-arginyl-L-lysyl-L-leucyl-L-leucyl-L-glutaminyl-L-α-aspartyl-L-isoleucyl-L-methionyl-L-seryl-L-argininamide
• L-Argininamide, N-acetyl-L-tyrosyl-D-arginyl-L-α-aspartyl-L-alanyl-L-isoleucyl-L-phenylalanyl-L-threonyl-L-asparaginyl-L-seryl-L-tyrosyl-L-arginyl-L-lysyl-L-valyl-L-leucylglycyl-L-glutaminyl-L-leu cyl-L-seryl-L-alanyl-L-arginyl-L-lysyl-L-leucyl-L-leucyl-L-glutaminyl-L-α-aspartyl-L-isoleucyl-L-methionyl-L-seryl-
• Somatoliberin (human pancreatic islet), N-acetyl-2-D-arginine-29-L-argininamide-30-de-L-glutamine-31-de-L-glutamine-32-deglycine-33-de-L-glutamic acid-34-de-L-serine-35-de-L-asparagine-36-de-L-glutamine-37-de-L-glutamic acid-38-de-L-arginine-39-deglycine-40-de-L-alanine-41-de-L-arginine-42-de-L-alanine-43-de-L-arginine-44-de-L-leucinamide-