蛋白激酶A 来源于牛心脏结构式
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常用名 | 蛋白激酶A 来源于牛心脏 | 英文名 | Protein serine/threonine kinase |
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| CAS号 | 9026-43-1 | 分子量 | 119.11916 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C4H9NO3 | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | N/A |
蛋白激酶A 来源于牛心脏用途蛋白激酶 A (PKA) 抑制激素敏感性脂肪酶从细胞质转移到储存液滴，并阻断脂解。调节细胞凋亡、线粒体呼吸和 ATP 合成。PKA 受蛋白酶钙蛋白酶调节。 |
| 中文名 | 蛋白质丝氨酸或苏氨酸激酶 (磷酸化) |
|---|---|
| 英文名 | Kinase(Phosphorylating), Protein Serine or Threonine |
| 英文别名 | 更多 |
| 分子式 | C4H9NO3 |
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| 分子量 | 119.11916 |
| 外观性状 | 冻干粉 |
| 储存条件 | -70°C密闭，避光，通风干燥处 |
| 稳定性 | Biochem/physiol Actions Serine-threonine protein kinase: these kinases appear to be involved in neurotransmitter release, control of stimulus-induced gene expression, and in the phosphorylation of microtubule related proteins. Unit Definition One unit will transfer 1.0 nanomole of phosphate from ATP to synapsin I per min at pH 7.0 at 30 °C. The peptide corresponds to the γ-2L subunit of the GABAA receptor. Physical form Solution in 50% glycerol containing 25 mM Tris-HCl, pH 7.5, 0.5 mM EDTA, 10 mM 2-mercaptoethanol, 10 μM 4-2-aminoethylbenzenesulfonyl fluoride, 0.01% leupeptin |
| 计算化学 | 1.疏水参数计算参考值（XlogP）:无 2.氢键供体数量:4 3.氢键受体数量:14 4.可旋转化学键数量:14 5.互变异构体数量:6 6.拓扑分子极性表面积221 7.重原子数量:62 8.表面电荷:0 9.复杂度:1790 10.同位素原子数量:0 11.确定原子立构中心数量:11 12.不确定原子立构中心数量:0 13.确定化学键立构中心数量:0 14.不确定化学键立构中心数量:0 15.共价键单元数量:1 |
| 更多 | 1. 性状:缓冲水甘油溶液。 2. 密度（g/mL,25℃）：未确定 3. 相对蒸汽密度（g/mL,空气=1）：未确定 4. 熔点（ºC）：未确定 5. 沸点（ºC,常压）：未确定 6. 沸点（ºC,5.2kPa）：未确定 7. 折射率：未确定 8. 闪点（ºC）：未确定 9. 比旋光度（º）：未确定 10. 自燃点或引燃温度（ºC）：未确定 11. 蒸气压（kPa,20ºC）：未确定 12. 饱和蒸气压（kPa,60ºC）：未确定 13. 燃烧热（KJ/mol）：未确定 14. 临界温度（ºC）：未确定 15. 临界压力（KPa）：未确定 16. 油水（辛醇/水）分配系数的对数值：未确定 17. 爆炸上限（%,V/V）：未确定 18. 爆炸下限（%,V/V）：未确定 19. 溶解性：不溶于水 |
| 个人防护装备 | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| 危险品运输编码 | NONH for all modes of transport |
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Expression and localization of five members of the testis-specific serine kinase (Tssk) family in mouse and human sperm and testis.
Mol. Hum. Reprod. 17(1) , 42-56, (2011) Members of the testis-specific serine/threonine kinases (Tssk) family may have a role in sperm differentiation in the testis and/or fertilization. To gain insight into the functional relevance of thes... |
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Hipk is an essential protein that promotes Notch signal transduction in theDrosophilaeye by inhibition of the global co-repressor Groucho
Dev. Biol. 325(1) , 263-72, (2009) Homeodomain interacting protein kinase (Hipk) is a member of a novel family of serine/threonine kinases. Extensive biochemical studies of vertebrate homologs, particularly Hipk2, have identified a gro... |
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Drosophila Smt3 negatively regulates JNK signaling through sequestering Hipk in the nucleus.
Development 138(12) , 2477-85, (2011) Post-translational modification by the small ubiquitin-related modifier (SUMO) is important for a variety of cellular and developmental processes. However, the precise mechanism(s) that connects sumoy... |
| MFCD00132121 |
