曲美替尼中间体结构式
|
常用名 | 曲美替尼中间体 | 英文名 | 3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethylpyrido[2,3-d]pyrimidine-2,4,7(1H,3H,8H)-trione |
|---|---|---|---|---|
| CAS号 | 871700-24-2 | 分子量 | 483.232 | |
| 密度 | 1.9±0.1 g/cm3 | 沸点 | 518.2±60.0 °C at 760 mmHg | |
| 分子式 | C18H15FIN3O4 | 熔点 | N/A | |
| MSDS | N/A | 闪点 | 267.2±32.9 °C |
| 中文名 | 曲美替尼中间体 |
|---|---|
| 英文名 | 3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethylpyr ido[2,3-d]pyrimidine-2,4,7(1H,3H,8H)-trione |
| 英文别名 | 更多 |
| 密度 | 1.9±0.1 g/cm3 |
|---|---|
| 沸点 | 518.2±60.0 °C at 760 mmHg |
| 分子式 | C18H15FIN3O4 |
| 分子量 | 483.232 |
| 闪点 | 267.2±32.9 °C |
| 精确质量 | 483.009125 |
| PSA | 86.23000 |
| LogP | 2.17 |
| 蒸汽压 | 0.0±1.4 mmHg at 25°C |
| 折射率 | 1.754 |
| 储存条件 | 2-8°C,避光干燥密封 |
|
~%
曲美替尼中间体 871700-24-2 |
| 文献:JAPAN TOBACCO INC.; SAKAI, Toshiyuki Patent: WO2005/121142 A1, 2005 ; Location in patent: Page/Page column 152-153 ; |
| 曲美替尼中间体上游产品 2 | |
|---|---|
| 曲美替尼中间体下游产品 1 | |
| cyclopropylthiadiazolamine |
| 3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethyl-1H,8H-pyrido[2,3-d]pyrimidine-2,4,7-trione |
| 3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethylpyrido[2,3-d]pyrimidine-2,4,7(1H,3H,8H)-trione |
| 3-cyclopropyl-[1,2,4]thiadiazol-5-ylamine |
| Pyrido[2,3-d]pyrimidine-2,4,7(1H,3H,8H)-trione, 3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethyl- |