金黄霉素B

更新时间:2024-01-17 23:43:48

金黄霉素B结构式
金黄霉素B结构式
品牌特惠专场
常用名 金黄霉素B 英文名 Chrysomycin B
CAS号 83852-56-6 分子量 496.506
密度 1.4±0.1 g/cm3 沸点 784.0±60.0 °C at 760 mmHg
分子式 C27H28O9 熔点 N/A
MSDS 中文版 美版 闪点 265.9±26.4 °C

 金黄霉素B用途


金霉素B是从链霉菌中分离出来的一种抗生素。金霉素B对人肺腺癌A549细胞株DNA损伤及拓扑异构酶II的抑制作用。金霉素B抑制小鼠移植性肿瘤的生长。

 金黄霉素B名称

中文名 金黄霉素B
英文名 Chrysomycin B
英文别名 更多

 金黄霉素B生物活性

描述 金霉素B是从链霉菌中分离出来的一种抗生素。金霉素B对人肺腺癌A549细胞株DNA损伤及拓扑异构酶II的抑制作用。金霉素B抑制小鼠移植性肿瘤的生长。
相关类别

 金黄霉素B物理化学性质

密度 1.4±0.1 g/cm3
沸点 784.0±60.0 °C at 760 mmHg
分子式 C27H28O9
分子量 496.506
闪点 265.9±26.4 °C
精确质量 496.173340
PSA 138.82000
LogP 4.99
外观性状 solid
蒸汽压 0.0±2.9 mmHg at 25°C
折射率 1.663
储存条件 2-8°C
水溶解性 DMF: soluble

 金黄霉素B安全信息

个人防护装备 Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
危险品运输编码 NONH for all modes of transport
WGK德国 3

 金黄霉素B文献4

更多文献
Angucyclines: Biosynthesis, mode-of-action, new natural products, and synthesis.

Nat. Prod. Rep. 29(2) , 264-325, (2012)

Covering: 1997 to 2010. The angucycline group is the largest group of type II PKS-engineered natural products, rich in biological activities and chemical scaffolds. This stimulated synthetic creativit...

A colorimetric microassay for the detection of agents that interact with DNA.

J. Nat. Prod. 55(11) , 1582-7, (1992)

A simple microtiter assay for the detection of compounds that bind DNA is described. Agents that displace methyl green from DNA are detected spectrophotometrically by a decrease in absorbance at 630 n...

The chemistry of the antibiotics chrysomycin A and B. Antitumor activity of chrysomycin A.

J. Antibiot. 35(9) , 1194-201, (1982)

The yellow antibiotic chrysomycin, isolated in crystalline form in 1955, is found to consist of two closely related components, a major one, chrysomycin A, and a minor one, chrysomycin B. They differ ...

 金黄霉素B英文别名

1,5-Anhydro-6-deoxy-1-(1-hydroxy-10,12-dimethoxy-8-methyl-6-oxo-6H-dibenzo[c,h]chromen-4-yl)-3-C-methylhexitol
Hexitol, 1,5-anhydro-6-deoxy-1-C-(1-hydroxy-10,12-dimethoxy-8-methyl-6-oxo-6H-benzo[d]naphtho[1,2-b]pyran-4-yl)-3-C-methyl-
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