氟哌啶醇癸酸酯

更新时间:2024-02-01 08:37:40

氟哌啶醇癸酸酯结构式
氟哌啶醇癸酸酯结构式
品牌特惠专场
常用名 氟哌啶醇癸酸酯 英文名 4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]-4-piperidyl decanoate
CAS号 74050-97-8 分子量 530.11400
密度 1.14 g/cm3 沸点 615.5ºC at 760 mmHg
分子式 C31H41ClFNO3 熔点 326.1ºC
MSDS N/A 闪点 326.1ºC

 氟哌啶醇癸酸酯用途


癸酸氟哌啶醇具有抗精神病活性。癸酸氟哌啶醇可用于精神分裂症和分裂情感障碍研究[1]。

 氟哌啶醇癸酸酯名称

中文名 4-(4-氯苯基)-1-[4-(4-氟苯基)-4-氧丁基]-4-哌啶癸酸盐
英文名 [4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] decanoate
中文别名 氟哌啶醇癸酸盐
英文别名 更多

 氟哌啶醇癸酸酯生物活性

描述 癸酸氟哌啶醇具有抗精神病活性。癸酸氟哌啶醇可用于精神分裂症和分裂情感障碍研究[1]。
相关类别
参考文献

[1]. R Beresford, et al. Haloperidol decanoate. A preliminary review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in psychosis. Drugs. 1987 Jan;33(1):31-49.

 氟哌啶醇癸酸酯物理化学性质

密度 1.14 g/cm3
沸点 615.5ºC at 760 mmHg
熔点 326.1ºC
分子式 C31H41ClFNO3
分子量 530.11400
闪点 326.1ºC
精确质量 529.27600
PSA 46.61000
LogP 8.05510
折射率 1.554
储存条件 -20°C
水溶解性 Practically insoluble in water, very soluble in ethanol (96 per cent), in methanol and in methylene chloride.

 氟哌啶醇癸酸酯毒性和生态

 氟哌啶醇癸酸酯安全信息

危险品运输编码 UN 3249
包装等级 III
危险类别 6.1(b)

 氟哌啶醇癸酸酯文献30

更多文献
Effectiveness of paliperidone palmitate vs haloperidol decanoate for maintenance treatment of schizophrenia: a randomized clinical trial.

JAMA 311(19) , 1978-87, (2014)

Long-acting injectable antipsychotics are used to reduce medication nonadherence and relapse in schizophrenia-spectrum disorders. The relative effectiveness of long-acting injectable versions of secon...

Maintenance treatment with long-acting injectable antipsychotics: comparing old with new.

JAMA 311(19) , 1973-4, (2014)

Ten year outcomes of outpatients with schizophrenia on conventional depot antipsychotics: a systematic chart review.

Int. Clin. Psychopharmacol. 28(5) , 261-6, (2013)

Long-term follow-up data of patients with schizophrenia on depot antipsychotics have been few and the longest follow-up period has been up to 7 years. We carried out a systematic chart review to exami...

 氟哌啶醇癸酸酯英文别名

HALOPERIDOL DECANOATE
KD 136
Haldol decanoas
EINECS 277-679-7
KD 16
UNII-AC20PJ4101
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