9-(4-甲氧基-2,3,6-三甲基苯基)-3,7-二甲基-2,4,6,8-丁烯酸

更新时间:2024-01-14 18:27:43

9-(4-甲氧基-2,3,6-三甲基苯基)-3,7-二甲基-2,4,6,8-丁烯酸结构式
9-(4-甲氧基-2,3,6-三甲基苯基)-3,7-二甲基-2,4,6,8-丁烯酸结构式
品牌特惠专场
常用名 9-(4-甲氧基-2,3,6-三甲基苯基)-3,7-二甲基-2,4,6,8-丁烯酸 英文名 13-cis-Acitretin
CAS号 69427-46-9 分子量 326.429
密度 1.1±0.1 g/cm3 沸点 521.3±38.0 °C at 760 mmHg
分子式 C21H26O3 熔点 228-230ºC
MSDS N/A 闪点 180.3±20.3 °C

 用途


Isoacitretin is an oral retinoid effective in the treatment of psoriasis.

 名称

中文名 9-(4-甲氧基-2,3,6-三甲基苯基)-3,7-二甲基-2,4,6,8-丁烯酸
英文名 13-cis Acitretin
英文别名 更多

 物理化学性质

密度 1.1±0.1 g/cm3
沸点 521.3±38.0 °C at 760 mmHg
熔点 228-230ºC
分子式 C21H26O3
分子量 326.429
闪点 180.3±20.3 °C
精确质量 326.188202
PSA 46.53000
LogP 5.73
蒸汽压 0.0±1.4 mmHg at 25°C
折射率 1.570
储存条件 Amber Vial, -80°C Freezer

 安全信息

危险品运输编码 NONH for all modes of transport

 文献26

更多文献
Comparative effectiveness of less commonly used systemic monotherapies and common combination therapies for moderate to severe psoriasis in the clinical setting.

J. Am. Acad. Dermatol. 71(6) , 1167-75, (2014)

The effectiveness of psoriasis therapies in real-world settings remains relatively unknown.We sought to compare the effectiveness of less commonly used systemic therapies and commonly used combination...

Acitretin exhibits inhibitory effects towards UDP-glucuronosyltransferase (UGT)1A9-mediated 4-methylumbelliferone (4-MU) and propofol glucuronidation reaction.

Pharmazie 68(6) , 449-52, (2013)

The present study aimed to evaluate the potential risk of drug-drug interactions associated with acitretin which is a drug for therapy of psoriasis approved by the Food and Drug Administration (FDA). ...

IgA pemphigus: case series with emphasis on therapeutic response.

J. Am. Acad. Dermatol. 70(1) , 200-1, (2014)

 英文别名

Soriatane
9-(4-methoxy-2,3,6-trimethyl-phenyl)-3,7-dimethyl-nona-2,4,6,8-tetraen-1-oic acid
9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid
(2E,4E,6E,8E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid
(2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid
9-(4-Isopropyl-phenyl)-guanin
Neo-Tigasone
Acetretinate
2,4,6,8-Nonatetraenoic acid, 9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-, (all-E)-
(all-E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid
Neotigason
2-amino-9-(4-isopropyl-phenyl)-1,9-dihydro-purin-6-one
Acitretin
2,4,6,8-Nonatetraenoic acid, 9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-, (2E,4E,6E,8E)-
(2E,4E,6E,8E)-3,7-dimethyl-9-[2,3,6-trimethyl-4-(methyloxy)phenyl]nona-2,4,6,8-tetraenoic acid
all-trans-acitretin
SNGP-201-04-E06