1-[[4-[5-[4-(2-甲基丙基)苯基]-1,2,4-噁二唑-3-基]苯基]甲基]-3-氮杂羧酸

• 常用名: 1-[[4-[5-[4-(2-甲基丙基)苯基]-1,2,4-噁二唑-3-基]苯基]甲基]-3-氮杂羧酸
• 英文名: Merck SIP Agonist
• CAS号: 635701-59-6
• 分子量: 391.46300
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₃H₂₅N₃O₃
• 熔点: N/A
• 闪点: N/A

用途

CAY10734 is an agonist of sphingosine-1-phosphate receptor 1 (S1P1). It selectively binds S1P1 over S1P2, S1P3, and S1P4 receptors but does also bind S1P5 receptors in radioligand binding assays. CAY10734 reduces peripheral blood lymphocytes and increases graft survival in a rat skin allograft model combination with cyclosporin A (CsA).

名称

• 中文名: 1-[[4-[5-[4-(2-甲基丙基)苯基]-1,2,4-噁二唑-3-基]苯基]甲基]-3-氮杂羧酸
• 英文名: 1-[[4-[5-[4-(2-methylpropyl)phenyl]-1,2,4-oxadiazol-3-yl]phenyl]methyl]azetidine-3-carboxylic acid

物理化学性质

• 分子式: C₂₃H₂₅N₃O₃
• 分子量: 391.46300
• 精确质量: 391.19000
• PSA: 79.46000
• LogP: 4.05640

安全信息

• 海关编码: 2934999090

海关

• 海关编码: 2934999090
• 中文概述: 2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途
• Summary: 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

英文别名

• 1,2,4-oxadiazole_based compound 26
• cc-147
• Merck SIP Agonist