P-[2-[[4-[(3-氯-4-氟苯基)氨基]-7-[[(3S)-四氢-3-呋喃基]氧基-6-喹唑啉基]氨基]-2-氧代乙基]膦酸二乙酯

• 常用名: P-[2-[[4-[(3-氯-4-氟苯基)氨基]-7-[[(3S)-四氢-3-呋喃基]氧基-6-喹唑啉基]氨基]-2-氧代乙基]膦酸二乙酯
• 英文名: (S)-DIETHYL 2-(4-(3-CHLORO-4-FLUOROPHENYLAMINO)-7-(TETRAHYDROFURAN-3-YLOXY)QUINAZOLIN-6-YLAMINO)-2-OXOETHYLPHOSPHONATE
• CAS号: 618061-76-0
• 分子量: 552.919
• 密度: 1.4±0.1 g/cm3
• 沸点: 709.9±60.0 °C at 760 mmHg
• 分子式: C₂₄H₂₇ClFN₄O₆P
• 熔点: N/A
• 闪点: 383.2±32.9 °C

名称

• 中文名: P-[2-[[4-[(3-氯-4-氟苯基)氨基]-7-[[(3S)-四氢-3-呋喃基]氧基-6-喹唑啉基]氨基]-2-氧代乙基]膦酸二乙酯
• 英文名: N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-2-diethoxyphosphorylacetamide

物理化学性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 709.9±60.0 °C at 760 mmHg
• 分子式: C₂₄H₂₇ClFN₄O₆P
• 分子量: 552.919
• 闪点: 383.2±32.9 °C
• 精确质量: 552.134094
• PSA: 134.20000
• LogP: 3.05
• InChIKey: FNGRCLBEXKFSST-INIZCTEOSA-N
• SMILES: CCOP(=O)(CC(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OC1CCOC1)OCC
• 蒸汽压: 0.0±2.3 mmHg at 25°C
• 折射率: 1.629
• 储存条件: 2-8°C，避光，保存于惰性气体中

英文别名

• Diethyl [2-({4-[(3-chloro-4-fluorophenyl)amino]-7-[(3S)-tetrahydro-3-furanyloxy]-6-quinazolinyl}amino)-2-oxoethyl]phosphonate
• (S)-diethyl 2-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-ylamino)-2-oxoethylphosphonate
• Diethyl {[4-(3-Chloro-4-Fluoro-Phenylamino)-7-((S)-Tetrahydrofuran-3-Yloxy)-Quinazolin-6-Ylcarbamoyl]-Methyl}-Phosphonate
• diethyl ((4-(3-chloro-4-fluorophenylamino)-7-(S)-(tetrahydrofuran-3-yloxy)quinazoline-6-ylcarbamoyl)methyl)phosphonate
• 4-[(3-chloro-4-fluorophenyl)amino]-6-[(diethoxyphosphoryl)acetylamino]-7-[(S)-(tetrahydrofuran-3-yl)oxy]quinazoline
• Phosphonic acid, P-[2-[[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]amino]-2-oxoethyl]-, diethyl ester
• QC-1120