延胡索乙素

常用名 延胡索乙素 英文名 tetrahydropalmatine hydrochloride
CAS号 6024-85-7 分子量 391.888
密度 N/A 沸点 482.9ºC at 760 mmHg
分子式 C21H26ClNO4 熔点 250-252ºC
MSDS延胡索乙素的MSDS|SDS|pdf下载 N/A 闪点 138.7ºC

 延胡索乙素用途


镇痛药。具有镇痛及催眠作用。用于内科病痛(如消化性溃肠痛)。产前阵痛。产后子宫缩痛。月经痛。头痛及失眠等症。

 延胡索乙素物理化学性质

[ 沸点 ]: 482.9ºC at 760 mmHg
[ 熔点 ]: 250-252ºC
[ 分子式 ]: C21H26ClNO4
[ 分子量 ]: 391.888
[ 闪点 ]: 138.7ºC
[ 精确质量 ]: 391.155029
[ PSA ]: 40.16000
[ LogP ]: 4.11640
[ 外观性状 ]: 固体

 延胡索乙素毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DR9840000
CHEMICAL NAME :
Berbine, 2,3,9,10-tetramethoxy-, hydrochloride, (+-)-
CAS REGISTRY NUMBER :
6024-85-7
LAST UPDATED :
199012
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C21-H25-N-O4.Cl-H
MOLECULAR WEIGHT :
391.93
WISWESSER LINE NOTATION :
T D6 B666 KN&TT&J GO1 HO1 PO1 QO1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1160 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 17,30,1983
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
121500 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FEPRA7 Federation Proceedings, Federation of American Societies for Experimental Biology. (Bethesda, MD) V.1-46, 1942-87. Volume(issue)/page/year: 5,163,1946