4-羟基咪达唑仑
4-羟基咪达唑仑结构式
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常用名 | 4-羟基咪达唑仑 | 英文名 | 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepin-4-ol |
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| CAS号 | 59468-85-8 | 分子量 | 341.76700 | |
| 密度 | 1.44g/cm3 | 沸点 | 550.6ºC at 760 mmHg | |
| 分子式 | C18H13ClFN3O | 熔点 | 186-187ºC | |
| MSDS | 美版 | 闪点 | 286.8ºC |
| 中文名 | 4-羟基咪达唑仑 |
|---|---|
| 英文名 | 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepin-4-ol |
| 中文别名 | 4-羟基咪哒唑伦 |
| 英文别名 | 更多 |
| 密度 | 1.44g/cm3 |
|---|---|
| 沸点 | 550.6ºC at 760 mmHg |
| 熔点 | 186-187ºC |
| 分子式 | C18H13ClFN3O |
| 分子量 | 341.76700 |
| 闪点 | 286.8ºC |
| 精确质量 | 341.07300 |
| PSA | 50.41000 |
| LogP | 3.25070 |
| 折射率 | 1.688 |
| 个人防护装备 | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| 危险品运输编码 | NONH for all modes of transport |
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4-羟基咪达唑仑 59468-85-8 |
| 文献：Xenobiotica, , vol. 32, # 11 p. 975 - 984 |
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4-羟基咪达唑仑 59468-85-8 |
| 文献：Xenobiotica, , vol. 38, # 4 p. 353 - 367 |
| 4-羟基咪达唑仑上游产品 1 | |
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| 4-羟基咪达唑仑下游产品 1 | |
CAS号81256-82-8|
A comparison of the metabolism of midazolam in C57BL/6J and hepatic reductase null (HRN) mice.
Biochem. Pharmacol. 92(4) , 701-11, (2014) The hepatic cytochrome P450 reductase null (HRN) mouse, which has no functional hepatic Cyp P450s, may represent a useful model for examining extra-hepatic P450-related oxidative metabolism. Here the ... |
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Systematic evaluation of commercially available ultra-high performance liquid chromatography columns for drug metabolite profiling: optimization of chromatographic peak capacity.
J. Chromatogr. A. 1374 , 122-33, (2014) The present study investigated the practical use of modern ultra-high performance liquid chromatography (UHPLC) separation techniques for drug metabolite profiling, aiming to develop a widely applicab... |
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Species differences and substrate specificity of CYP3A heteroactivation by efavirenz.
Xenobiotica 45(4) , 345-52, (2015) 1. The purpose of this study was to clarify species differences in the heteroactivation of CYP3A substrates by efavirenz, which is known from clinical studies to activate midazolam 1'-hydroxylation, a... |
| 8-Chloro-6-(2-fluorophenyl)-4-hydroxy-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine |
| 8-Chloro-6-(2-fluorophenyl)-4-hydroxy-4H-imidazo[1,5a][1,4]bezodiazepine |
| 4-OH-Mdz |
| 4-hydroxy-MDZ |
| 8-chloro-(2-fluoro-phenyl)-1-methyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepin-4-ol |
| 4-Hydroxy Midazolam |
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