2-甲氧基-4-硝基-1-(三氟甲基)苯

更新时间：2025-08-26 21:11:38

2-甲氧基-4-硝基-1-(三氟甲基)苯结构式	常用名	2-甲氧基-4-硝基-1-(三氟甲基)苯	英文名	2-Methoxy-4-nitro-1-(trifluoromethyl)benzene
	CAS号	453560-74-2	分子量	221.13300
	密度	N/A	沸点	N/A
	分子式	C₈H₆F₃NO₃	熔点	N/A
	MSDS	N/A	闪点	N/A

中文名	2-甲氧基-4-硝基-1-(三氟甲基)苯
英文名	2-Methoxy-4-nitro-1-(trifluoromethyl)benzene
英文别名	更多

分子式	C₈H₆F₃NO₃
分子量	221.13300
精确质量	221.03000
PSA	55.05000
LogP	3.14540
InChIKey	UDEARCRKLPPYAU-UHFFFAOYSA-N
SMILES	COc1cc([N+](=O)[O-])ccc1C(F)(F)F
储存条件	室温

三氟碘甲烷

2314-97-8

2-碘基-5-硝基苯甲醚

5458-84-4

~43%

2-甲氧基-4-硝基-1-(三氟甲基)苯

453560-74-2

文献：Potashman, Michele H.; Bready, James; Coxon, Angela; Demelfi Jr., Thomas M.; DiPietro, Lucian; Doerr, Nicholas; Elbaum, Daniel; Estrada, Juan; Gallant, Paul; Germain, Julie; Gu, Yan; Harmange, Jean-Christophe; Kaufman, Stephen A.; Kendall, Rick; Kim, Joseph L.; Kumar, Gondi N.; Long, Alexander M.; Neervannan, Seshadri; Patel, Vinod F.; Polverino, Anthony; Rose, Paul; Van Der Plas, Simon; Whittington, Douglas; Zanon, Roger; Zhao, Huilin Journal of Medicinal Chemistry, 2007 , vol. 50, # 18 p. 4351 - 4373

2-碘基-5-硝基苯甲醚

5458-84-4

(三氟甲基)三甲基硅烷

81290-20-2

~73%

2-甲氧基-4-硝基-1-(三氟甲基)苯

453560-74-2

文献：Talamas, Francisco X.; Abbot, Sarah C.; Anand, Shalini; Brameld, Ken A.; Carter, David S.; Chen, Jun; Davis, Dana; De Vicente, Javier; Fung, Amy D.; Gong, Leyi; Harris, Seth F.; Inbar, Petra; Labadie, Sharada S.; Lee, Eun K.; Lemoine, Remy; Le Pogam, Sophie; Leveque, Vincent; Li, Jim; McIntosh, Joel; Najera, Isabel; Park, Jaehyeon; Railkar, Aruna; Rajyaguru, Sonal; Sangi, Michael; Schoenfeld, Ryan C.; Staben, Leanna R.; Tan, Yunchou; Taygerly, Joshua P.; Villasenor, Armando G.; Weller, Paul E. Journal of Medicinal Chemistry, 2014 , vol. 57, # 5 p. 1914 - 1931

氯代二氟乙酸甲酯

1514-87-0

2-碘基-5-硝基苯甲醚

5458-84-4

~51%

2-甲氧基-4-硝基-1-(三氟甲基)苯

453560-74-2

文献：Brotherton-Pleiss, Christine E.; Caroon, Joan Marie; Lopez-Tapia, Francisco Javier Patent: US2010/160388 A1, 2010 ; Location in patent: Page/Page column 64-65 ; US 20100160388 A1

氟磺酰二氟乙酸甲酯

680-15-9

2-溴-5-硝基苯甲醚

77337-82-7

2-甲氧基-4-硝基-1-(三氟甲基)苯

453560-74-2

文献：VERTEX PHARMACEUTICALS INCORPORATED Patent: US2010/168094 A1, 2010 ; Location in patent: Page/Page column 69; 70 ; US 20100168094 A1

2-碘基-5-硝基苯甲醚

5458-84-4

2-甲氧基-4-硝基-1-(三氟甲基)苯

453560-74-2

文献：AMGEN INC Patent: WO2004/85425 A1, 2004 ; Location in patent: Page 98-99 ; WO 2004/085425 A1

3,3-diisopropyl...

1448037-95-3

(三氟甲基)三甲基硅烷

81290-20-2

~64%

2-甲氧基-4-硝基-1-(三氟甲基)苯

453560-74-2

文献：Hafner, Andreas; Braese, Stefan Advanced Synthesis and Catalysis, 2013 , vol. 355, # 5 p. 996 - 1000

2-甲氧基-4-硝基-1-(三氟甲基)苯上游产品 6
CAS号2314-97-8 三氟碘甲烷 CAS号5458-84-4 2-碘基-5-硝基苯甲醚 CAS号81290-20-2 (三氟甲基)三甲基硅烷 CAS号1514-87-0 氯代二氟乙酸甲酯
CAS号680-15-9 氟磺酰二氟乙酸甲酯 CAS号77337-82-7 2-溴-5-硝基苯甲醚
2-甲氧基-4-硝基-1-(三氟甲基)苯下游产品 3
CAS号52427-05-1 2-溴-5-硝基苯酚 CAS号612498-85-8 5-Nitro-2-trifl... CAS号106877-20-7 3-甲氧基-4-(三氟甲基)苯胺