DABCYL-TNF-α-EDANS (-4 to +6) (human) trifluoroacetate salt

• 常用名: DABCYL-TNF-α-EDANS (-4 to +6) (human) trifluoroacetate salt
• 英文名: DABCYL-TNF-α-EDANS (-4 to +6) (human) trifluoroacetate salt
• CAS号: 396716-14-6
• 分子量: 1573.776
• 密度: 1.5±0.1 g/cm3
• 沸点: N/A
• 分子式: C₇₀H₁₀₄N₂₂O₁₈S
• 熔点: N/A
• 闪点: N/A

用途

DABCYL-TNF-α-EDANS (-4 to +6) (human) 是 tumor necrosis factor convertase (TACE) 的 FRET 肽底物。

名称

• 英文名: DABCYL-TNF-α-EDANS (-4 to +6) (human)

生物活性

• 描述: DABCYL-TNF-α-EDANS (-4 to +6) (human) 是 tumor necrosis factor convertase (TACE) 的 FRET 肽底物。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Liepinsh E, et al. NMR structure of the netrin-like domain (NTR) of human type I procollagen C-proteinase enhancer defines structural consensus of NTR domains and assesses potential proteinase inhibitory activity and ligand binding. J Biol Chem. 2003 Jul 11;278(28):25982-9.

物理化学性质

• 密度: 1.5±0.1 g/cm3
• 分子式: C₇₀H₁₀₄N₂₂O₁₈S
• 分子量: 1573.776
• 精确质量: 1572.761963
• LogP: 7.36
• 折射率: 1.664

英文别名

• 3,6,9,12,15,18,21-Heptaazahexacosa-3,6,9,12,15,18,21-heptaene-1,26-diimidic acid, 2,14-bis[3-[(aminoiminomethyl)amino]propyl]-23-[[(2S)-2-[[(2S)-2-[[4-[(E)-2-[4-(dimethylamino)phenyl]diazenyl]benzoyl] ;amino]-1-hydroxy-4-methylpentylidene]amino]-1-hydroxypropylidene]amino]-4,7,10,13,16,19,22-heptahydroxy-5,8,11-tris(hydroxymethyl)-20-methyl-17-(1-methylethyl)-N-[2-[(5-sulfo-1-naphthalenyl)amino]e thyl]-, (2S,5S,8S,11S,14S,17S,20S,23S)-
• (2S,5S,8S,11S,14S,17S,20S,23S)-2,14-Bis(3-carbamimidamidopropyl)-23-{[(2S)-2-({(2S)-2-[(4-{(E)-[4-(dimethylamino)phenyl]diazenyl}benzoyl)amino]-1-hydroxy-4-methylpentylidene}amino)-1-hydroxypropyliden ;e]amino}-4,7,10,13,16,19,22-heptahydroxy-5,8,11-tris(hydroxymethyl)-17-isopropyl-20-methyl-N-{2-[(5-sulfo-1-naphthyl)amino]ethyl}-3,6,9,12,15,18,21-heptaazahexacosa-3,6,9,12,15,18,21-heptaene-1,26- ;diimidic acid
• DABCYL-Leu-Ala-Gln-Ala-Val-Arg-Ser-Ser-Ser-Arg-EDANS
• TACE FRET Substrate I