2-(3AR,4S,6R,6AS)-6-(5-胺基-6-氯-2-丙硫基-4-嘧啶基)氨基四氢-2,2-二甲基-4H-环戊烯并-1,3-二氧杂环戊烷-4-基]氧]-乙醇 (替卡格雷中间体12)

• 常用名: 2-(3AR,4S,6R,6AS)-6-(5-胺基-6-氯-2-丙硫基-4-嘧啶基)氨基四氢-2,2-二甲基-4H-环戊烯并-1,3-二氧杂环戊烷-4-基]氧]-乙醇 (替卡格雷中间体12)
• 英文名: 2-[[(3aR,4S,6R,6aS)-6-[[5-Amino-6-chloro-2-(propylthio)-4-pyrimidinyl]amino]tetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]-ethanol
• CAS号: 376608-74-1
• 分子量: 418.939
• 密度: 1.4±0.1 g/cm3
• 沸点: 598.9±50.0 °C at 760 mmHg
• 分子式: C₁₇H₂₇ClN₄O₄S
• 熔点: N/A
• 闪点: 316.0±30.1 °C

名称

• 中文名: 2-[[(3aR,4S,6R,6aS)-6-[[5-氨基-6-氯-2-(丙硫基)-4-嘧啶基]氨基]四氢-2,2-二甲基-4H-环戊烯并-1,3-二恶茂-4-基]氧基]乙醇
• 英文名: 2-[[(3aR,4S,6R,6aS)-6-[[5-amino-6-chloro-2-(propylthio)-4-pyrimidinyl]amino]tetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]-ethanol
• 中文别名: 替卡格雷中间体12 | 替格瑞洛中间体12

物理化学性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 598.9±50.0 °C at 760 mmHg
• 分子式: C₁₇H₂₇ClN₄O₄S
• 分子量: 418.939
• 闪点: 316.0±30.1 °C
• 精确质量: 418.144165
• PSA: 140.28000
• LogP: 4.45
• 蒸汽压: 0.0±1.8 mmHg at 25°C
• 折射率: 1.607
• 储存条件: 室温，干燥

英文别名

• 2-{[(3aR,4S,6R,6aS)-6-{[5-Amino-6-chloro-2-(propylsulfanyl)-4-pyrimidinyl]amino}-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl]oxy}ethanol
• Ticagrelor intermediate 12
• 2-{[(3aR,4S,6R,6aS)-6-{[5-Amino-6-chloro-2-(propylsulfanyl)-4-pyr imidinyl]amino}-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]diox ol-4-yl]oxy}ethanol
• Ethanol, 2-[[(3aR,4S,6R,6aS)-6-[[5-amino-6-chloro-2-(propylthio)-4-pyrimidinyl]amino]tetrahydro-2,2-dimethyl-4H-cyclopenta[d]-1,3-dioxol-4-yl]oxy]-