R-116010

• 常用名: R-116010
• 英文名: R-116010
• CAS号: 355860-40-1
• 分子量: 377.506
• 密度: 1.2±0.1 g/cm3
• 沸点: 569.7±60.0 °C at 760 mmHg
• 分子式: C₂₁H₂₃N₅S
• 熔点: N/A
• 闪点: 298.4±32.9 °C

R-116010用途

A potent CYP26A1 inhibitor with IC50 of 10 nM, potently inhibits all-trans-retinoic acid metabolism in intact T47D cells with IC50 of 8.7 nM; enhances the ATRA-mediated antiproliferative activity in a concentration-dependent manner, significantly inhibits the growth of murine oestrogen-independent TA3-Ha mammary tumour in vivo.

R-116010名称

• 英文名: N1-(1,3-Benzothiazol-2-yl)-4-[(1S)-1-(1H-imidazol-1-yl)propyl]-N2,N2-dimethyl-1,2-benzenediamine

R-116010物理化学性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 569.7±60.0 °C at 760 mmHg
• 分子式: C₂₁H₂₃N₅S
• 分子量: 377.506
• 闪点: 298.4±32.9 °C
• 精确质量: 377.167419
• LogP: 4.19
• 蒸汽压: 0.0±1.6 mmHg at 25°C
• 折射率: 1.669

R-116010英文别名

• 1,2-Benzenediamine, N1-2-benzothiazolyl-4-[(1S)-1-(1H-imidazol-1-yl)propyl]-N2,N2-dimethyl-
• N1-(1,3-Benzothiazol-2-yl)-4-[(1S)-1-(1H-imidazol-1-yl)propyl]-N2,N2-dimethyl-1,2-benzenediamine