Fluphenazine enanthate结构式
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常用名 | Fluphenazine enanthate | 英文名 | Fluphenazine enanthate |
|---|---|---|---|---|
| CAS号 | 2746-81-8 | 分子量 | 549.69100 | |
| 密度 | 1.181g/cm3 | 沸点 | 629.4ºC at 760mmHg | |
| 分子式 | C29H38F3N3O2S | 熔点 | N/A | |
| MSDS | N/A | 闪点 | 334.4ºC |
Fluphenazine enanthate用途Fluphenazine enanthate 是第一种长效抗精神病药物,用于治疗精神分裂症。 |
| 中文名 | 氟奋乃静庚酸酯 |
|---|---|
| 英文名 | 2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethyl heptanoate |
| 英文别名 | 更多 |
| 描述 | Fluphenazine enanthate 是第一种长效抗精神病药物,用于治疗精神分裂症。 |
|---|---|
| 相关类别 | |
| 体内研究 | 氟奋乃静对映体(2,4,8mg/kg；IM)对回避行为的抑制作用分别持续16、23和28天[1]。氟奋乃静(8mg/kg)的饮酒行为在给药后24小时内几乎完全被抑制[1]。氟奋乃嗪(8 mg/kg)在大鼠体内产生短暂的体重损失[1]。动物模型：Wistar品系雄性成年大鼠54只[1]剂量：2、4、8mg/kg给药：中指数(IM)结果：3种剂量的氟哌嗪分别在16、23、28d时对回避行为有明显抑制作用。 |
| 参考文献 |
| 密度 | 1.181g/cm3 |
|---|---|
| 沸点 | 629.4ºC at 760mmHg |
| 分子式 | C29H38F3N3O2S |
| 分子量 | 549.69100 |
| 闪点 | 334.4ºC |
| 精确质量 | 549.26400 |
| PSA | 61.32000 |
| LogP | 6.77020 |
| 蒸汽压 | 9.41E-16mmHg at 25°C |
| 折射率 | 1.544 |
| 危险品运输编码 | UN 3249 |
|---|---|
| 包装等级 | III |
| 危险类别 | 6.1(b) |
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Ten year outcomes of outpatients with schizophrenia on conventional depot antipsychotics: a systematic chart review.
Int. Clin. Psychopharmacol. 28(5) , 261-6, (2013) Long-term follow-up data of patients with schizophrenia on depot antipsychotics have been few and the longest follow-up period has been up to 7 years. We carried out a systematic chart review to exami... |
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Treatment of schizophrenia with depot preparations of fluphenazine, haloperidol, and risperidone among inpatients at state-operated psychiatric facilities.
Schizophr. Res. 119(1-3) , 153-9, (2010) This study aimed to characterize the inpatient utilization of depot antipsychotics.The characteristics of adults with schizophrenia or schizoaffective disorder, hospitalized for at least 28 days, and ... |
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Multiple congenital abnormalities in a newborn boy associated with maternal use of fluphenazine enanthate and other drugs during pregnancy.
Acta Paediatr. Scand. 71(2) , 335-8, (1982) A boy was born with a short sloping forehead, wide metopic suture, persistent metopic fontanelle, telecanthus, ocular hypertelorism, nystagmoid eye movements, bilateral cleft lip and palate, imperfora... |
| Fluphenazine enantate |
| 2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethyl heptanoate |
| Fluphenazinenanthat |
| Fluphenanzin-aenanthat |
| 2-[4-[3-[2-(Trifluoromethyl)phenothiazin-10-yl]propyl]-1-piperazinyl]ethyl heptanoate |
| Fluphenazin-aenanthsaeureester |
| 4-<3-<2-Trifluormethyl-phenothiazinyl-(10)>-propyl>-1-(2-hydroxy-ethyl)-piperazin-heptanoat |
| 1-heptanoyloxy-2-{4-[3-(2-trifluoromethyl-phenothiazin-10-yl)-propyl]-piperazin-1-yl}-ethane |
| Moditen-retard |
| Prolixin Enanthate |
| fluphenazine enanthate |
| fluphenazine O-enantate |
| Eutimox |
| EINECS 220-385-0 |
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