1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHO[N-(4-CARBOXYBUTANOYL)ETHANOLAMINE]

• 常用名: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHO[N-(4-CARBOXYBUTANOYL)ETHANOLAMINE]
• 英文名: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHO[N-(4-CARBOXYBUTANOYL)ETHANOLAMINE]
• CAS号: 228706-30-7
• 分子量: 858.13300
• 密度: N/A
• 沸点: N/A
• 分子式: C₄₆H₈₄NO₁₁P
• 熔点: N/A
• 闪点: N/A

用途

DOPE-GA可用于脂质体的配制,并用于药物递送的研究[1]。

名称

• 英文名: 5-[2-[[(2R)-2,3-di(octadec-9-enoyloxy)propoxy]-hydroxyphosphoryl]oxyethylamino]-5-oxopentanoic acid

生物活性

• 描述: DOPE-GA可用于脂质体的配制,并用于药物递送的研究[1]。
• 相关类别:
  研究领域 >> 癌症
• 参考文献:

  [1]. Cuvillier O, et al. Liposomal ET-18-OCH(3) induces cytochrome c-mediated apoptosis independently of CD95 (APO-1/Fas) signaling. Blood. 1999 Nov 15;94(10):3583-92.

  [2]. Perkins WR, et al. Novel therapeutic nano-particles (lipocores): trapping poorly water soluble compounds. Int J Pharm. 2000 Apr 25;200(1):27-39.

物理化学性质

• 分子式: C₄₆H₈₄NO₁₁P
• 分子量: 858.13300
• 精确质量: 857.57800
• PSA: 188.06000
• LogP: 12.86140
• InChIKey: CSYWTOSHKUIHLT-PLQHGIRQSA-N
• SMILES: CCCCCCCCC=CCCCCCCCC(=O)OCC(COP(=O)(O)OCCNC(=O)CCCC(=O)O)OC(=O)CCCCCCCC=CCCCCCCCC

英文别名

• 9,11,15-Trioxa-6-aza-10-phosphatritriacont-24-enoicacid,10-hydroxy-5,16-dioxo-13-[[(9Z)-1-oxo-9-octadecenyl]oxy]-,10-oxide,(13R,24Z)-(9CI)
• 9,11,15-Trioxa-6-aza-10-phosphatritriacont-24-enoicacid,10-hydroxy-5,16-dioxo-13-[[(9Z)-1-oxo-9-octadecen-1-yl]oxy]-,10-oxide,(13R,24Z)