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扎拉果酸三钠盐

更新时间:2025-09-24 12:44:33

扎拉果酸三钠盐结构式
扎拉果酸三钠盐结构式
品牌特惠专场
常用名 扎拉果酸三钠盐 英文名 Zaragozic acid A trisodium salt
CAS号 144541-82-2 分子量 756.677
密度 N/A 沸点 N/A
分子式 C35H43Na3O14 熔点 N/A
MSDS 美版 闪点 N/A

 扎拉果酸三钠盐用途


扎拉果酸三钠盐是哺乳动物,真菌和啤酒酵母鲨烯合酶的有效抑制剂。Zaragozic acid A三钠盐是角鲨烯合酶抑制剂,在灵长类动物中可能产生较低的血浆胆固醇水平。我们还提供游离酸形式Zaragozic Acid A,以避免与盐水解相关的稳定性问题。 Zaragozic acid A trisodium salt is a potent inhibitor of mammalian, fungal and|Saccharomyces cervisiae|squalene synthase. Being a squalene synthase inhibitor, Zaragozic acid A trisodium salt may produce lower plasma cholesterol levels in primates. We offer also offer the free acid form, Zaragozic Acid A , to avoid stability problems associated with hydrolysis of the salt.

 扎拉果酸三钠盐名称

中文名 扎拉果酸三钠盐
英文名 Zaragozic acid A trisodium salt
英文别名 更多

 扎拉果酸三钠盐物理化学性质

分子式 C35H43Na3O14
分子量 756.677
精确质量 756.234619
储存条件 -20°C储存
水溶解性 Soluble in ethanol (10 mg/ml), and DMSO (10 mg/ml, heating may be required).

 扎拉果酸三钠盐安全信息

个人防护装备 Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
危险品运输编码 NONH for all modes of transport
WGK德国 3

 扎拉果酸三钠盐文献4

更多文献
Differential roles of the mevalonate pathway in the development and survival of mouse Purkinje cells in culture.

Mol. Neurobiol. 51 , 1116-29, (2015)

The cerebellum is an important locus for motor learning and higher cognitive functions, and Purkinje cells constitute a key component of its circuit. Biochemically, significant turnover of cholesterol...

OX40 complexes with phosphoinositide 3-kinase and protein kinase B (PKB) to augment TCR-dependent PKB signaling.

J. Immunol. 186 , 3547-55, (2011)

T lymphocyte activation requires signal 1 from the TCR and signal 2 from costimulatory receptors. For long-lasting immunity, growth and survival signals imparted through the Akt/protein kinase B (PKB)...

Mechanisms for autophagy modulation by isoprenoid biosynthetic pathway inhibitors in multiple myeloma cells.

Oncotarget 6 , 41535-49, (2015)

Multiple myeloma (MM) is characterized by the production of monoclonal protein (MP). We have shown previously that disruption of the isoprenoid biosynthetic pathway (IBP) causes a block in MP secretio...

 扎拉果酸三钠盐英文别名

Zaragozic acid A is also known as Squalestatin A, Squalestatin S1, and L 694599.
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