![]() 扎拉果酸三钠盐结构式
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常用名 | 扎拉果酸三钠盐 | 英文名 | Zaragozic acid A trisodium salt |
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CAS号 | 144541-82-2 | 分子量 | 756.677 | |
密度 | N/A | 沸点 | N/A | |
分子式 | C35H43Na3O14 | 熔点 | N/A | |
MSDS | 美版 | 闪点 | N/A |
扎拉果酸三钠盐用途扎拉果酸三钠盐是哺乳动物,真菌和啤酒酵母鲨烯合酶的有效抑制剂。Zaragozic acid A三钠盐是角鲨烯合酶抑制剂,在灵长类动物中可能产生较低的血浆胆固醇水平。我们还提供游离酸形式Zaragozic Acid A,以避免与盐水解相关的稳定性问题。 Zaragozic acid A trisodium salt is a potent inhibitor of mammalian, fungal and|Saccharomyces cervisiae|squalene synthase. Being a squalene synthase inhibitor, Zaragozic acid A trisodium salt may produce lower plasma cholesterol levels in primates. We offer also offer the free acid form, Zaragozic Acid A , to avoid stability problems associated with hydrolysis of the salt. |
中文名 | 扎拉果酸三钠盐 |
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英文名 | Zaragozic acid A trisodium salt |
英文别名 | 更多 |
分子式 | C35H43Na3O14 |
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分子量 | 756.677 |
精确质量 | 756.234619 |
储存条件 | -20°C储存 |
水溶解性 | Soluble in ethanol (10 mg/ml), and DMSO (10 mg/ml, heating may be required). |
个人防护装备 | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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危险品运输编码 | NONH for all modes of transport |
WGK德国 | 3 |
Differential roles of the mevalonate pathway in the development and survival of mouse Purkinje cells in culture.
Mol. Neurobiol. 51 , 1116-29, (2015) The cerebellum is an important locus for motor learning and higher cognitive functions, and Purkinje cells constitute a key component of its circuit. Biochemically, significant turnover of cholesterol... |
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OX40 complexes with phosphoinositide 3-kinase and protein kinase B (PKB) to augment TCR-dependent PKB signaling.
J. Immunol. 186 , 3547-55, (2011) T lymphocyte activation requires signal 1 from the TCR and signal 2 from costimulatory receptors. For long-lasting immunity, growth and survival signals imparted through the Akt/protein kinase B (PKB)... |
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Mechanisms for autophagy modulation by isoprenoid biosynthetic pathway inhibitors in multiple myeloma cells.
Oncotarget 6 , 41535-49, (2015) Multiple myeloma (MM) is characterized by the production of monoclonal protein (MP). We have shown previously that disruption of the isoprenoid biosynthetic pathway (IBP) causes a block in MP secretio... |
Zaragozic acid A is also known as Squalestatin A, Squalestatin S1, and L 694599. |