酸浆苦素L

• 常用名: 酸浆苦素L
• 英文名: Physalin L
• CAS号: 113146-74-0
• 分子量: 528.548
• 密度: 1.5±0.1 g/cm3
• 沸点: 831.1±65.0 °C at 760 mmHg
• 分子式: C₂₈H₃₂O₁₀
• 熔点: N/A
• 闪点: 280.4±27.8 °C

酸浆苦素L用途

Physalin L抑制LPS诱导的巨噬细胞产生NO,平均抑制率为70.97%。抗炎活性[1]。

酸浆苦素L名称

• 中文名: 酸浆苦味素L
• 英文名: (1S,2S,3R,5R,6S,7R,14R,15S,18R,21S,22R,25S)-5,7,18-Trihydroxy-1,14,21,25-tetramethyl-4,20,23-trioxaheptacyclo[20.3.1.12,5.03,18.03,21.06,15.09,14]heptacosa-8,10-diene-13,19,24,27-tetrone

酸浆苦素L生物活性

• 描述: Physalin L抑制LPS诱导的巨噬细胞产生NO,平均抑制率为70.97%。抗炎活性[1]。
• 相关类别:
  信号通路 >> 免疫及炎症 >> 一氧化氮合酶
• 参考文献:

  [1]. Long Ji, et al. Physalins with anti-inflammatory activity are present in Physalis alkekengi var. franchetii and can function as Michael reaction acceptors. Steroids. 2012 Apr;77(5):441-7.

酸浆苦素L物理化学性质

• 密度: 1.5±0.1 g/cm3
• 沸点: 831.1±65.0 °C at 760 mmHg
• 分子式: C₂₈H₃₂O₁₀
• 分子量: 528.548
• 闪点: 280.4±27.8 °C
• 精确质量: 528.199524
• PSA: 156.66000
• LogP: 2.07
• 蒸汽压: 0.0±0.6 mmHg at 25°C
• 折射率: 1.659

酸浆苦素L英文别名

• 1,17:2,6-Dimethano-8H-naphtho[1,2-f]furo[3,4-b:2,3-c']bisoxocin-4,8,11,19(1H,10H)-tetrone, 2,3,6,6a,8a,9,10a,10b,12,16,16a,17-dodecahydro-8a,16,17-trihydroxy-2,3,6a,10b-tetramethyl-, (1R,2S,3S,6R,6aS,8aS,10aS,10bR,16R,16aS,17R,18aR)-
• (1S,2R,3R,5R,6S,7R,14R,15S,18S,21S,22R,25S)-5,7,18-Trihydroxy-1,14,21,25-tetramethyl-4,20,23-trioxaheptacyclo[20.3.1.1.0.0.0.0]heptacosa-8,10-diene-13,19,24,27-tetrone