HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL926886

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 2008
Volume: 51
Issue: 7
First Page: 2244
Last Page: 2253
DOI: 10.1021/jm800012w

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
	logIC50	=	1.51	-
0.059	IC50	=	59	nM
	logIC50	=	1.96	-
0.0195	IC50	=	19.5	nM
	logIC50	=	0.84	-
0.0522	IC50	=	52.2	nM
	logIC50	=	1.72	-
0.5929	IC50	=	592.9	nM
	logIC50	=	1.14	-

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL1058014

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem. Lett.
Year: 2009
Volume: 19
Issue: 15
First Page: 4284
Last Page: 4287
DOI: 10.1016/j.bmcl.2009.05.065

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
300	IC50	>	300000	nM	Outside typical range
300	IC50	>	300000	nM	Outside typical range
80	IC50	=	80000	nM
20.7	IC50	=	20700	nM
109	IC50	=	109000	nM	Outside typical range
300	IC50	>	300000	nM	Outside typical range
300	IC50	>	300000	nM	Outside typical range
300	IC50	>	300000	nM	Outside typical range

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL1058015

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2009
Volume: 19
Issue: 15
First Page: 4284
Last Page: 4287
DOI: 10.1016/j.bmcl.2009.05.065

Standard Type	Standard Relation	Standard Value
Ratio IC50	=	19.3
Ratio IC50	=	102
Ratio IC50	=	50
Ratio IC50	=	16.6
Ratio IC50	=	14.6
Ratio IC50	=	14.1
Ratio IC50	=	19.6

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL1058013

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem. Lett.
Year: 2009
Volume: 19
Issue: 15
First Page: 4284
Last Page: 4287
DOI: 10.1016/j.bmcl.2009.05.065

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
157	IC50	=	157000	nM	Outside typical range
155	IC50	=	155000	nM	Outside typical range
4.78	IC50	=	4780	nM
1.47	IC50	=	1470	nM
7.62	IC50	=	7620	nM
169	IC50	=	169000	nM	Outside typical range
33	IC50	=	33000	nM
122	IC50	=	122000	nM	Outside typical range

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL921413

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 2008
Volume: 51
Issue: 7
First Page: 2244
Last Page: 2253
DOI: 10.1021/jm800012w

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
0.137	IC50	=	137	nM
0.00102	IC50	=	1.02	nM
0.00116	IC50	=	1.16	nM
0.0288	IC50	=	28.8	nM
	logIC50	=	1.46	-
122.67	IC50	=	122670	nM	Outside typical range
0.0598	IC50	=	59.8	nM
	logIC50	=	1.78	-
0.014	IC50	=	14	nM
0.00289	IC50	=	2.89	nM
0.00895	IC50	=	8.95	nM
0.00329	IC50	=	3.29	nM
0.00437	IC50	=	4.37	nM
0.00358	IC50	=	3.58	nM
0.0207	IC50	=	20.7	nM
0.00369	IC50	=	3.69	nM
	logIC50	=	0.57	-

960403-07-0 靶点实验数据