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954792-78-0 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:dCTP pyrophosphatase 1
External ID: CHEMBL4057014
Protocol: N/A
Comment: Journal: Bioorg Med Chem Lett
Year: 2017
Volume: 27
Issue: 16
First Page: 3897
Last Page: 3904
DOI: 10.1016/j.bmcl.2017.06.038

Target ChEMBL ID: CHEMBL3769292
ChEMBL Target Name: dCTP pyrophosphatase 1
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned
Standard TypeStandard RelationStandard ValueStandard Units
Inhibition=92%
Inhibition=2%
Inhibition=86%
Inhibition=97%
Inhibition=97%
Inhibition=91%
Inhibition=93%
Inhibition=47%
Inhibition=10%
Inhibition=89%
Inhibition=73%
Inhibition=8%
Inhibition=89%
Inhibition=69%
Inhibition=93%
Inhibition=87%
Inhibition=98%
Inhibition=96%
Inhibition=53%
Inhibition=95%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:dCTP pyrophosphatase 1
External ID: CHEMBL4057013
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg Med Chem Lett
Year: 2017
Volume: 27
Issue: 16
First Page: 3897
Last Page: 3904
DOI: 10.1016/j.bmcl.2017.06.038

Target ChEMBL ID: CHEMBL3769292
ChEMBL Target Name: dCTP pyrophosphatase 1
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
0.94IC50=940nM
0.84IC50=840nM
0.55IC50=550nM
0.047IC50=47nM
1.91IC50=1910nM
1.1IC50=1100nM
1.3IC50=1300nM
0.98IC50=980nM
0.62IC50=620nM
2.1IC50=2100nM
0.37IC50=370nM
2.6IC50=2600nM