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952958-85-9 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Patatin-like phospholipase domain-containing protein 2
External ID: CHEMBL4727005
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg Med Chem
Year: 2020
Volume: 28
Issue: 16
First Page: 115610
Last Page: 115610
DOI: 10.1016/j.bmc.2020.115610

Target ChEMBL ID: CHEMBL3425391
ChEMBL Target Name: Patatin-like phospholipase domain-containing protein 2
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard UnitsData Validity Comment
130IC50=130000nMOutside typical range
200IC50>200000nMOutside typical range
70IC50=70000nM
200IC50=200000nMOutside typical range
200IC50=200000nMOutside typical range
200IC50>200000nMOutside typical range
5IC50=5000nM
50IC50=50000nM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Patatin-like phospholipase domain-containing protein 2
External ID: CHEMBL4727006
Protocol: N/A
Comment: Journal: Bioorg Med Chem
Year: 2020
Volume: 28
Issue: 16
First Page: 115610
Last Page: 115610
DOI: 10.1016/j.bmc.2020.115610

Target ChEMBL ID: CHEMBL3425391
ChEMBL Target Name: Patatin-like phospholipase domain-containing protein 2
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned
Standard TypeStandard RelationStandard ValueStandard Units
Inhibition=35%
Inhibition=81%
Inhibition=40%
Inhibition=65%
Inhibition=77%
Inhibition=87%
Inhibition=98%
Inhibition=52%
Inhibition=63%
Inhibition=70%