HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：BindingDB 靶标：N/A

External ID: BindingDB_7518_1

Protocol: N/A

Comment: Compounds with any of Ki, IC50, Kd, or EC50 activity value <= 10uM are labeled as "Active".
If multiple measurements are available for a given compound, it is labeled as "Active" if any of the measurements meet the criterion. Activity values are checked in the order of Ki, IC50, Kd, and EC50. The first entry that meets the above activity threshold is used to determine "Standard Type", "Standard Relation", and "PubChem Standard Value". Otherwise, the first non-empty entry will be used to set those values.

Standard Type	PubChem Standard Value	Ki	Target Accession(s)	Ligand	Target
Ki	0.00169	1.69	P21728	BDBM86180	D(1A) dopamine receptor
Ki	0.03394	33.94	P21728	BDBM199154	D(1A) dopamine receptor
Ki	0.02653	26.53	P14416	BDBM199154	D(2) dopamine receptor

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：IUPHAR-DB 靶标：D1 receptor (Dopamine receptors) [Homo sapiens]

External ID: 214_Human

Protocol: The International Union of Basic and Clinical Pharmacology/British Pharmacological Society (IUPHAR/BPS) Guide to PHARMACOLOGY Database (GtoPdb) uses expert subcommittees to collate peer-reviewed information from the published literature regarding individual protein targets, and describes the pharmacology, genetics, function and anatomy of each target. Its pages provide a richly curated overview of the pharmacology of receptors, ion channels, enzymes and other target types, which can be found by following the external link to the GtoPdb website.

Comment: The data collected focuses on ligands at human receptors. Data are provided at rat or mouse orthologues where there are significant species differences, or where data are not yet available at the human target.

Information on individual experimental protocols can be found in the primary references listed for each ligand.

Affinity data are expressed as pKi [-log(Ki)], pKd [-log(Kd)], pIC50 [-log(IC50)], pEC50 [-log(EC50)], pKB [-log(KB)], pA2 or as a micromolar concentration range. In most cases the original concentration can be found in the primary reference.

pKi_min	pKi_max	pKd_min	pKd_max	pEC50_min	pEC50_max	Type	Action	Reference (PubMed ID)
7.1	7.1					Antagonist	Antagonist	1826762
5.7	5.7					Agonist	Partial agonist	1826762
6.2	6.8					Agonist	Partial agonist	1826762,7525564
6.2	6.2					Agonist	Full agonist	1826762
		9.5	9.5			Antagonist	Antagonist	2144334
6.9	6.9					Antagonist	Antagonist	1826762
7.4	7.4					Agonist	Full agonist	1826762
7.1	7.1					Antagonist	Antagonist
5.3	6.2					Agonist	Full agonist	1826762,7525564
5.6	5.6					Agonist	Full agonist	1826762
7	7					Antagonist	Antagonist	15357957
				9.7	9.7	Agonist	Biased agonist	25660762
4.3	5.6					Agonist	Full agonist	1826762,7525564
		9.5	9.5			Antagonist	Antagonist	2168520
7	7					Antagonist	Antagonist	1826762
7	8.4					Antagonist	Antagonist	1826762,7525564
				6.8	6.8	Agonist	Agonist	16318870
6.2	6.2					Agonist	Partial agonist	1826762,12388666
7.6	8.2					Antagonist	Antagonist	1826762,18308814
8.3	8.3					Antagonist	Antagonist	7862709

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：IUPHAR-DB 靶标：D5 receptor (Dopamine receptors) [Homo sapiens]

External ID: 218_Human

Protocol: The International Union of Basic and Clinical Pharmacology/British Pharmacological Society (IUPHAR/BPS) Guide to PHARMACOLOGY Database (GtoPdb) uses expert subcommittees to collate peer-reviewed information from the published literature regarding individual protein targets, and describes the pharmacology, genetics, function and anatomy of each target. Its pages provide a richly curated overview of the pharmacology of receptors, ion channels, enzymes and other target types, which can be found by following the external link to the GtoPdb website.

Comment: The data collected focuses on ligands at human receptors. Data are provided at rat or mouse orthologues where there are significant species differences, or where data are not yet available at the human target.

Information on individual experimental protocols can be found in the primary references listed for each ligand.

Affinity data are expressed as pKi [-log(Ki)], pKd [-log(Kd)], pIC50 [-log(IC50)], pEC50 [-log(EC50)], pKB [-log(KB)], pA2 or as a micromolar concentration range. In most cases the original concentration can be found in the primary reference.

pKi_min	pKi_max	pKd_min	pKd_max	pEC50_min	pEC50_max	Type	Action	Reference (PubMed ID)
5.3	5.3					Antagonist	Antagonist	1826762
6	7.5					Agonist	Full agonist	1826762,12388666
6.9	6.9					Antagonist	Antagonist	1826762
7	7					Agonist	Partial agonist	1826762
4.9	4.9					Agonist	Full agonist	1826762
6.3	6.3					Agonist	Full agonist	1826762
5.9	5.9					Agonist	Full agonist	1826762
7.8	7.8					Agonist	Full agonist	1826762
6.4	7.8					Agonist	Partial agonist	1826762,12388666
7.7	7.7					Agonist	Full agonist	12388666
6	6					Agonist	Full agonist	1826762
9.4	9.4					Antagonist	Antagonist	1826762
7.6	7.6					Antagonist	Antagonist	1826762
6.6	6.6					Agonist	Full agonist	1826762
		9.2	9.2			Antagonist	Antagonist	8051291
5.6	5.6					Antagonist	Antagonist	1826762
8.1	8.1					Antagonist	Antagonist	1826762
8.3	8.3					Antagonist	Antagonist	1826762
				6.6	6.6	Agonist	Agonist	16318870
6.3	6.3					Agonist	Full agonist	1826762,12388666

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：5-hydroxytryptamine receptor 2A

External ID: CHEMBL2343277

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem.
Year: 2013
Volume: 21
Issue: 4
First Page: 856
Last Page: 868
DOI: 10.1016/j.bmc.2012.12.016

Target ChEMBL ID: CHEMBL224
ChEMBL Target Name: Serotonin 2a (5-HT2a) receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
	Ki				Not Determined
	Ki				Not Determined
	Ki				Not Determined
	Ki				Not Determined
	Ki				Not Determined
	Ki				Not Determined
	Ki				Not Determined
	Ki				Not Determined
	Ki				Not Determined
0.48	Ki	=	480	nM
	Ki				Not Determined
	Ki				Not Determined
	Ki				Not Determined

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：D(1A) dopamine receptor

External ID: CHEMBL2343276

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem.
Year: 2013
Volume: 21
Issue: 4
First Page: 856
Last Page: 868
DOI: 10.1016/j.bmc.2012.12.016

Target ChEMBL ID: CHEMBL2056
ChEMBL Target Name: Dopamine D1 receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
	EC50				Not Determined
0.13	EC50	=	130	nM
	Emax	=	100	%
1.35	EC50	=	1350	nM
	EC50				Not Determined
15.97	EC50	=	15970	nM
	Emax	=	35.6	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：D(1A) dopamine receptor

External ID: CHEMBL2342847

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem.
Year: 2013
Volume: 21
Issue: 4
First Page: 856
Last Page: 868
DOI: 10.1016/j.bmc.2012.12.016

Target ChEMBL ID: CHEMBL2056
ChEMBL Target Name: Dopamine D1 receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
	IC50				Not Determined
	Imax				Not Determined
	IC50				Not Determined
21.27	IC50	=	21270	nM
	Imax	=	83.5	%
17.37	IC50	=	17370	nM
	Imax	=	78.2	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：BindingDB 靶标：N/A

External ID: BindingDB_7518_2

Protocol: N/A

Comment: Compounds with any of Ki, IC50, Kd, or EC50 activity value <= 10uM are labeled as "Active".
If multiple measurements are available for a given compound, it is labeled as "Active" if any of the measurements meet the criterion. Activity values are checked in the order of Ki, IC50, Kd, and EC50. The first entry that meets the above activity threshold is used to determine "Standard Type", "Standard Relation", and "PubChem Standard Value". Otherwise, the first non-empty entry will be used to set those values.

Standard Type	PubChem Standard Value	IC50	EC50	Target Accession(s)	Ligand	Target
IC50	0.14	140		P21728	BDBM199158	D(1A) dopamine receptor

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：5-hydroxytryptamine receptor 1A

External ID: CHEMBL2342846

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem.
Year: 2013
Volume: 21
Issue: 4
First Page: 856
Last Page: 868
DOI: 10.1016/j.bmc.2012.12.016

Target ChEMBL ID: CHEMBL214
ChEMBL Target Name: Serotonin 1a (5-HT1a) receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
	EC50				Not Determined
	Emax				Not Determined
	EC50				Not Determined
0.19	EC50	=	190	nM
	EC50				Not Determined
13.5	EC50	=	13500	nM
	Emax	=	80.7	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：BindingDB 靶标：N/A

External ID: BindingDB_8179_1

Protocol: N/A

Comment: Compounds with any of Ki, IC50, Kd, or EC50 activity value <= 10uM are labeled as "Active".
If multiple measurements are available for a given compound, it is labeled as "Active" if any of the measurements meet the criterion. Activity values are checked in the order of Ki, IC50, Kd, and EC50. The first entry that meets the above activity threshold is used to determine "Standard Type", "Standard Relation", and "PubChem Standard Value". Otherwise, the first non-empty entry will be used to set those values.

Standard Type	PubChem Standard Value	Ki	IC50	Target Accession(s)	Ligand	Target
Ki	0.00124	1.24	2.52	P21728	BDBM86180	D(1A) dopamine receptor
Ki	0.18241	182.41	323.79	P21728	BDBM50387556	D(1A) dopamine receptor
Ki	0.59989	599.89	758.03	P08908	BDBM50387556	5-hydroxytryptamine receptor 1A
Ki	0.33438	334.38	1727.6	P14416	BDBM235773	D(2) dopamine receptor
Ki	0.24804	248.04	483.67	P21728	BDBM235777	D(1A) dopamine receptor

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：D(2) dopamine receptor

External ID: CHEMBL2342830

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem.
Year: 2013
Volume: 21
Issue: 4
First Page: 856
Last Page: 868
DOI: 10.1016/j.bmc.2012.12.016

Target ChEMBL ID: CHEMBL217
ChEMBL Target Name: Dopamine D2 receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
	Imax	=	94.6	%
	Imax				Not Determined
	IC50				Not Determined
18.73	IC50	=	18730	nM
	IC50				Not Determined
1	IC50	=	1000	nM
	Imax	=	58.9	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：5-hydroxytryptamine receptor 2A

External ID: CHEMBL2343281

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem.
Year: 2013
Volume: 21
Issue: 4
First Page: 856
Last Page: 868
DOI: 10.1016/j.bmc.2012.12.016

Target ChEMBL ID: CHEMBL224
ChEMBL Target Name: Serotonin 2a (5-HT2a) receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
Inhibition				Not Determined
Inhibition	=	100	%
Inhibition	=	45.6	%
Inhibition	=	46.6	%
Inhibition	=	68.8	%
Inhibition				Not Determined
Inhibition	=	20.9	%
Inhibition	=	40.6	%
Inhibition	=	40.4	%
Inhibition	=	29.7	%
Inhibition	=	49.1	%
Inhibition	=	10.9	%
Inhibition	=	40.5	%
Inhibition	=	38	%
Inhibition	=	59.1	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：IUPHAR-DB 靶标：Kir2.3 (Inwardly rectifying potassium channels) [Homo sapiens]

External ID: 432_Human

Protocol: The International Union of Basic and Clinical Pharmacology/British Pharmacological Society (IUPHAR/BPS) Guide to PHARMACOLOGY Database (GtoPdb) uses expert subcommittees to collate peer-reviewed information from the published literature regarding individual protein targets, and describes the pharmacology, genetics, function and anatomy of each target. Its pages provide a richly curated overview of the pharmacology of receptors, ion channels, enzymes and other target types, which can be found by following the external link to the GtoPdb website.

Comment: The data collected focuses on ligands at human receptors. Data are provided at rat or mouse orthologues where there are significant species differences, or where data are not yet available at the human target.

Information on individual experimental protocols can be found in the primary references listed for each ligand.

Affinity data are expressed as pKi [-log(Ki)], pKd [-log(Kd)], pIC50 [-log(IC50)], pEC50 [-log(EC50)], pKB [-log(KB)], pA2 or as a micromolar concentration range. In most cases the original concentration can be found in the primary reference.

pKi_min	pKi_max	pIC50_min	pIC50_max	Concentration range (muM)	Type	Action	Reference (PubMed ID)
6.7	7.4				Gating inhibitor	Antagonist	10200419,10896660,7576658
				50.0-300.0	Channel blocker	Antagonist	7576658
				50.0-1000.0	Channel blocker	Antagonist	7969496
		5	5	3.0-500.0	Channel blocker	Antagonist	8051145,12032359,8034048

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：D(1A) dopamine receptor

External ID: CHEMBL2343280

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem.
Year: 2013
Volume: 21
Issue: 4
First Page: 856
Last Page: 868
DOI: 10.1016/j.bmc.2012.12.016

Target ChEMBL ID: CHEMBL2056
ChEMBL Target Name: Dopamine D1 receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
0.231	Ki	=	231	nM
0.0034	Ki	=	3.4	nM
0.05	Ki	=	50	nM
0.443	Ki	=	443	nM
0.022	Ki	=	22	nM
0.0025	Ki	=	2.5	nM
0.0173	Ki	=	17.3	nM
	Ki				Not Determined
0.06	Ki	=	60	nM
5	Ki	>	5000	nM
0.0045	Ki	=	4.5	nM
0.0063	Ki	=	6.3	nM
	Ki				Not Determined
0.53	Ki	=	530	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：D(2) dopamine receptor

External ID: CHEMBL2343279

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem.
Year: 2013
Volume: 21
Issue: 4
First Page: 856
Last Page: 868
DOI: 10.1016/j.bmc.2012.12.016

Target ChEMBL ID: CHEMBL217
ChEMBL Target Name: Dopamine D2 receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
5	Ki	>	5000	nM
0.011	Ki	=	11	nM
0.305	Ki	=	305	nM
	Ki				Not Determined
0.214	Ki	=	214	nM
	Ki				Not Determined
0.147	Ki	=	147	nM
	Ki				Not Determined
5	Ki	>	5000	nM
	Ki				Not Determined
0.091	Ki	=	91	nM
0.145	Ki	=	145	nM
	Ki				Not Determined
5	Ki	>	5000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：5-hydroxytryptamine receptor 1A

External ID: CHEMBL2343278

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem.
Year: 2013
Volume: 21
Issue: 4
First Page: 856
Last Page: 868
DOI: 10.1016/j.bmc.2012.12.016

Target ChEMBL ID: CHEMBL214
ChEMBL Target Name: Serotonin 1a (5-HT1a) receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
5	Ki	>	5000	nM
5	Ki	>	5000	nM
0.149	Ki	=	149	nM
	Ki				Not Determined
	Ki				Not Determined
	Ki				Not Determined
5	Ki	>	5000	nM
	Ki				Not Determined
5	Ki	>	5000	nM
	Ki				Not Determined
	Ki				Not Determined
0.908	Ki	=	908	nM
	Ki				Not Determined
	Ki				Not Determined

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：D(1A) dopamine receptor

External ID: CHEMBL2343284

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem.
Year: 2013
Volume: 21
Issue: 4
First Page: 856
Last Page: 868
DOI: 10.1016/j.bmc.2012.12.016

Target ChEMBL ID: CHEMBL2056
ChEMBL Target Name: Dopamine D1 receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
Inhibition				Not Determined
Inhibition				Not Determined
Inhibition	=	99.8	%
Inhibition	=	98.3	%
Inhibition	=	98.8	%
Inhibition	=	100	%
Inhibition	=	99.1	%
Inhibition	=	99.5	%
Inhibition	=	88.8	%
Inhibition	=	39.8	%
Inhibition	=	98.7	%
Inhibition	=	78.9	%
Inhibition	=	99.2	%
Inhibition	=	84.1	%
Inhibition	=	95.2	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：D(2) dopamine receptor

External ID: CHEMBL2343283

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem.
Year: 2013
Volume: 21
Issue: 4
First Page: 856
Last Page: 868
DOI: 10.1016/j.bmc.2012.12.016

Target ChEMBL ID: CHEMBL217
ChEMBL Target Name: Dopamine D2 receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
Inhibition				Not Determined
Inhibition	=	100	%
Inhibition	=	97.5	%
Inhibition	=	88.7	%
Inhibition	=	88.8	%
Inhibition				Not Determined
Inhibition	=	93.4	%
Inhibition	=	90.5	%
Inhibition	=	71.5	%
Inhibition	=	20.5	%
Inhibition	=	78	%
Inhibition	=	20.4	%
Inhibition	=	90.9	%
Inhibition	=	63.2	%
Inhibition	=	79.8	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：5-hydroxytryptamine receptor 1A

External ID: CHEMBL2343282

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem.
Year: 2013
Volume: 21
Issue: 4
First Page: 856
Last Page: 868
DOI: 10.1016/j.bmc.2012.12.016

Target ChEMBL ID: CHEMBL214
ChEMBL Target Name: Serotonin 1a (5-HT1a) receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
Inhibition	=	100	%
Inhibition				Not Determined
Inhibition	=	89.3	%
Inhibition	=	84.4	%
Inhibition	=	97.4	%
Inhibition				Not Determined
Inhibition	=	14.2	%
Inhibition	=	64.2	%
Inhibition	=	55.4	%
Inhibition	=	30.4	%
Inhibition	=	82.8	%
Inhibition	=	25.5	%
Inhibition	=	71.1	%
Inhibition	=	50.5	%
Inhibition	=	60.5	%

95191-55-2 靶点实验数据