HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Thromboxane-A synthase

External ID: CHEMBL814406

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1987
Volume: 30
Issue: 6
First Page: 1036
Last Page: 1040
DOI: 10.1021/jm00389a013

Target ChEMBL ID: CHEMBL4028
ChEMBL Target Name: Thromboxane-A synthase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

Standard Type	Standard Relation	Standard Value	Standard Units
Inhibition	=	100	%
Inhibition	=	100	%
Inhibition	=	95	%
Inhibition	=	85	%
Inhibition	=	56	%
Inhibition	=	100	%
Inhibition	=	100	%
Inhibition	=	93	%
Inhibition	=	98	%
Inhibition	=	100	%
Inhibition	=	97	%
Inhibition	=	100	%
Inhibition	=	89	%
Inhibition	=	100	%
Inhibition	=	83	%
Inhibition	=	100	%
Inhibition	=	95	%
Inhibition	=	65	%
Inhibition	=	82	%
Inhibition	=	96	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Rattus norvegicus

External ID: CHEMBL792583

Protocol: N/A

Comment: Journal: J Med Chem
Year: 1987
Volume: 30
Issue: 6
First Page: 1036
Last Page: 1040
DOI: 10.1021/jm00389a013

Target ChEMBL ID: CHEMBL376
ChEMBL Target Name: Rattus norvegicus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type
Activity
Activity
Activity
Activity
Activity
Activity
Activity
Activity

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Thromboxane-A synthase

External ID: CHEMBL814405

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1987
Volume: 30
Issue: 6
First Page: 1036
Last Page: 1040
DOI: 10.1021/jm00389a013

Target ChEMBL ID: CHEMBL4028
ChEMBL Target Name: Thromboxane-A synthase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
0.05	IC50	=	50	nM
8	IC50	=	8000	nM
0.04	IC50	=	40	nM
0.4	IC50	=	400	nM
0.3	IC50	=	300	nM
0.07	IC50	=	70	nM
0.2	IC50	=	200	nM
0.2	IC50	=	200	nM
1.5	IC50	=	1500	nM

95082-35-2 靶点实验数据