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95082-25-0 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Rattus norvegicus
External ID: CHEMBL792580
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 1987
Volume: 30
Issue: 6
First Page: 1036
Last Page: 1040
DOI: 10.1021/jm00389a013

Target ChEMBL ID: CHEMBL376
ChEMBL Target Name: Rattus norvegicus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeActivity Comment
ActivityNot Determined
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Thromboxane-A synthase
External ID: CHEMBL814406
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 1987
Volume: 30
Issue: 6
First Page: 1036
Last Page: 1040
DOI: 10.1021/jm00389a013

Target ChEMBL ID: CHEMBL4028
ChEMBL Target Name: Thromboxane-A synthase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned
Standard TypeStandard RelationStandard ValueStandard Units
Inhibition=100%
Inhibition=100%
Inhibition=95%
Inhibition=85%
Inhibition=56%
Inhibition=100%
Inhibition=100%
Inhibition=93%
Inhibition=98%
Inhibition=100%
Inhibition=97%
Inhibition=100%
Inhibition=89%
Inhibition=100%
Inhibition=83%
Inhibition=100%
Inhibition=95%
Inhibition=65%
Inhibition=82%
Inhibition=96%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Plasmodium falciparum
External ID: CHEMBL4888485
Protocol: N/A
Comment: Target ChEMBL ID: CHEMBL364
ChEMBL Target Name: Plasmodium falciparum
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Data Source: MMV Malaria Hit Generation Library
Standard TypeStandard RelationStandard ValueStandard UnitsData Validity Comment
Z score=1.23
Inhibition=-8%
Z score=1.2
Inhibition=-11%Outside typical range
Z score=-0.08
Inhibition=1%
Z score=2.72
Inhibition=-24%Outside typical range
Z score=0.82
Inhibition=-5%
Z score=1.48
Inhibition=-12%Outside typical range
Z score=-10.93
Inhibition=57%
Z score=-0.31
Inhibition=2%
Z score=1.21
Inhibition=-8%
Z score=-1.25
Inhibition=7%