HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL1780990

Protocol: N/A

Comment: Journal: Bioorg Med Chem Lett
Year: 2011
Volume: 21
Issue: 11
First Page: 3282
Last Page: 3285
DOI: 10.1016/j.bmcl.2011.04.027

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
780	Ki	=	780000	nM
430	Ki	=	430000	nM
680	Ki	=	680000	nM
410	Ki	=	410000	nM
500	Ki	=	500000	nM
1200	Ki	=	1200000	nM
900	Ki	=	900000	nM
2000	Ki	>	2000000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Lysyl oxidase homolog 2

External ID: CHEMBL3997541

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: ACS Med Chem Lett
Year: 2017
Volume: 8
Issue: 4
First Page: 423
Last Page: 427
DOI: 10.1021/acsmedchemlett.7b00014

Target ChEMBL ID: CHEMBL3714029
ChEMBL Target Name: Lysyl oxidase homolog 2
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
3.62	IC50	=	3620	nM
47	IC50	=	47000	nM
1.11	IC50	=	1110	nM
0.719	IC50	=	719	nM
3.54	IC50	=	3540	nM
1.22	IC50	=	1220	nM
0.066	IC50	=	66	nM
0.309	IC50	=	309	nM
100	IC50	>	100000	nM
1.18	IC50	=	1180	nM
0.67	IC50	=	670	nM
6.04	IC50	=	6040	nM
0.321	IC50	=	321	nM
8.21	IC50	=	8210	nM
31	IC50	>	31000	nM
100	IC50	>	100000	nM
0.902	IC50	=	902	nM
0.999	IC50	=	999	nM
0.385	IC50	=	385	nM
0.203	IC50	=	203	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL1781100

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2011
Volume: 21
Issue: 11
First Page: 3282
Last Page: 3285
DOI: 10.1016/j.bmcl.2011.04.027

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
990	Ki	=	990000	nM
760	Ki	=	760000	nM
890	Ki	=	890000	nM
2000	Ki	>	2000000	nM
2000	Ki	>	2000000	nM
510	Ki	=	510000	nM
970	Ki	=	970000	nM

93071-65-9 靶点实验数据