HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mus musculus

External ID: CHEMBL721014

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1985
Volume: 28
Issue: 1
First Page: 28
Last Page: 31
DOI: 10.1021/jm00379a007

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
ED50	=	31.5	mg.kg-1
ED50	>	200	mg.kg-1
ED50	=	68.8	mg.kg-1
ED50	=	60.9	mg.kg-1
ED50	=	116.7	mg.kg-1
ED50	>	200	mg.kg-1
ED50	>	150	mg.kg-1
ED50	>	37.5	mg.kg-1
ED50	>	200	mg.kg-1
ED50	=	51.6	mg.kg-1
ED50	=	64.4	mg.kg-1
ED50	=	100	mg.kg-1
ED50	=	150	mg.kg-1
ED50	>	75	mg.kg-1
ED50	=	131.9	mg.kg-1
ED50	=	183.3	mg.kg-1
ED50	>	150	mg.kg-1
ED50	=	137.5	mg.kg-1
ED50	>	37.5	mg.kg-1
ED50	>	200	mg.kg-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mus musculus

External ID: CHEMBL724598

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1985
Volume: 28
Issue: 1
First Page: 28
Last Page: 31
DOI: 10.1021/jm00379a007

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
ED50	=	39.8	mg.kg-1
ED50	>	200	mg.kg-1
ED50	>	100	mg.kg-1
ED50	=	138	mg.kg-1
ED50	>	200	mg.kg-1
ED50	>	200	mg.kg-1
ED50	>	200	mg.kg-1
ED50	>	50	mg.kg-1
ED50	>	200	mg.kg-1
ED50	=	133.3	mg.kg-1
ED50	=	92.9	mg.kg-1
ED50	=	185.7	mg.kg-1
ED50	=	200	mg.kg-1
ED50	>	100	mg.kg-1
ED50	>	200	mg.kg-1
ED50	>	200	mg.kg-1
ED50	>	200	mg.kg-1
ED50	>	200	mg.kg-1
ED50	>	50	mg.kg-1
ED50	>	200	mg.kg-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL848510

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1985
Volume: 28
Issue: 1
First Page: 28
Last Page: 31
DOI: 10.1021/jm00379a007

Standard Type	Activity Comment
Ratio	Not Active
Ratio	Not Active
Ratio	Not Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Rattus norvegicus

External ID: CHEMBL787496

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1985
Volume: 28
Issue: 1
First Page: 28
Last Page: 31
DOI: 10.1021/jm00379a007

Target ChEMBL ID: CHEMBL376
ChEMBL Target Name: Rattus norvegicus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
LD50	=	565	mg.kg-1
LD50	>	400	mg.kg-1
LD50	=	300	mg.kg-1
LD50	=	300	mg.kg-1
LD50	>	400	mg.kg-1
LD50	=	162.5	mg.kg-1
LD50	>	400	mg.kg-1
LD50	=	300	mg.kg-1
LD50	=	300	mg.kg-1
LD50	=	366.7	mg.kg-1
LD50	=	333.3	mg.kg-1
LD50	=	400	mg.kg-1
LD50	=	333.3	mg.kg-1
LD50	>	400	mg.kg-1
LD50	>	400	mg.kg-1
LD50	>	400	mg.kg-1
LD50	=	300	mg.kg-1
LD50	>	400	mg.kg-1
LD50	>	400	mg.kg-1
LD50	=	300	mg.kg-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mus musculus

External ID: CHEMBL723426

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1985
Volume: 28
Issue: 1
First Page: 28
Last Page: 31
DOI: 10.1021/jm00379a007

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
RD50	=	21.9	mg kg-1
RD50	=	150	mg kg-1
RD50	=	24.7	mg kg-1
RD50	=	49.5	mg kg-1
RD50	=	75	mg kg-1
RD50	>	200	mg kg-1
RD50	=	126.9	mg kg-1
RD50	=	127.6	mg kg-1
RD50	>	50	mg kg-1
RD50	=	45.1	mg kg-1
RD50	=	68.8	mg kg-1
RD50	=	66.7	mg kg-1
RD50	>	75	mg kg-1
RD50	=	131.9	mg kg-1
RD50	=	68.8	mg kg-1
RD50	>	200	mg kg-1
RD50	>	75	mg kg-1
RD50	=	150	mg kg-1
RD50	>	150	mg kg-1
RD50	=	150	mg kg-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mus musculus

External ID: CHEMBL725371

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1985
Volume: 28
Issue: 1
First Page: 28
Last Page: 31
DOI: 10.1021/jm00379a007

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
ND50	=	31.5	mg kg-1
ND50	>	200	mg kg-1
ND50	>	75	mg kg-1
ND50	=	111.5	mg kg-1
ND50	>	200	mg kg-1
ND50	>	200	mg kg-1
ND50	>	150	mg kg-1
ND50	>	37.5	mg kg-1
ND50	>	150	mg kg-1
ND50	=	106.5	mg kg-1
ND50	=	57.9	mg kg-1
ND50	=	115.8	mg kg-1
ND50	>	200	mg kg-1
ND50	>	75	mg kg-1
ND50	=	140.5	mg kg-1
ND50	>	200	mg kg-1
ND50	>	150	mg kg-1
ND50	>	200	mg kg-1
ND50	>	37.5	mg kg-1
ND50	>	200	mg kg-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mus musculus

External ID: CHEMBL719558

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1985
Volume: 28
Issue: 1
First Page: 28
Last Page: 31
DOI: 10.1021/jm00379a007

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
ED50	=	35.6	mg.kg-1
ED50	>	200	mg.kg-1
ED50	=	75	mg.kg-1
ED50	=	81.5	mg.kg-1
ED50	=	183.3	mg.kg-1
ED50	>	200	mg.kg-1
ED50	>	200	mg.kg-1
ED50	>	50	mg.kg-1
ED50	>	200	mg.kg-1
ED50	=	93.8	mg.kg-1
ED50	=	87.5	mg.kg-1
ED50	=	78.6	mg.kg-1
ED50	>	200	mg.kg-1
ED50	>	100	mg.kg-1
ED50	>	200	mg.kg-1
ED50	>	200	mg.kg-1
ED50	=	158	mg.kg-1
ED50	>	200	mg.kg-1
ED50	>	50	mg.kg-1
ED50	>	200	mg.kg-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mus musculus

External ID: CHEMBL724592

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1985
Volume: 28
Issue: 1
First Page: 28
Last Page: 31
DOI: 10.1021/jm00379a007

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
ED50	=	34.4	mg.kg-1
ED50	>	200	mg.kg-1
ED50	=	75	mg.kg-1
ED50	=	93	mg.kg-1
ED50	=	183.3	mg.kg-1
ED50	>	200	mg.kg-1
ED50	>	200	mg.kg-1
ED50	>	50	mg.kg-1
ED50	>	200	mg.kg-1
ED50	=	128.6	mg.kg-1
ED50	=	90	mg.kg-1
ED50	=	116.7	mg.kg-1
ED50	=	90	mg.kg-1
ED50	>	200	mg.kg-1
ED50	>	100	mg.kg-1
ED50	>	200	mg.kg-1
ED50	>	75	mg.kg-1
ED50	>	200	mg.kg-1
ED50	=	186	mg.kg-1
ED50	>	200	mg.kg-1

93040-68-7 靶点实验数据