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92014-77-2 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:3-oxoacyl-[acyl-carrier-protein] synthase 3
External ID: CHEMBL891698
Protocol: N/A
Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2007
Volume: 17
Issue: 4
First Page: 879
Last Page: 883
DOI: 10.1016/j.bmcl.2006.11.067

Target ChEMBL ID: CHEMBL1795135
ChEMBL Target Name: 3-oxoacyl-[acyl-carrier-protein] synthase 3
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned
Standard TypeStandard RelationStandard ValueStandard Units
Activity=90%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Beta-ketoacyl-[acyl-carrier-protein] synthase III
External ID: CHEMBL891697
Protocol: N/A
Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2007
Volume: 17
Issue: 4
First Page: 879
Last Page: 883
DOI: 10.1016/j.bmcl.2006.11.067

Target ChEMBL ID: CHEMBL4968
ChEMBL Target Name: Beta-ketoacyl-ACP-synthase III
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned
Standard TypeActivity Comment
ActivityNot Active
ActivityNot Active
ActivityNot Active
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Escherichia coli
External ID: CHEMBL891699
Protocol: N/A
Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2007
Volume: 17
Issue: 4
First Page: 879
Last Page: 883
DOI: 10.1016/j.bmcl.2006.11.067

Target ChEMBL ID: CHEMBL354
ChEMBL Target Name: Escherichia coli
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
MIC=6.6ug.mL-1
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:3-oxoacyl-[acyl-carrier-protein] synthase 3
External ID: CHEMBL891691
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem. Lett.
Year: 2007
Volume: 17
Issue: 4
First Page: 879
Last Page: 883
DOI: 10.1016/j.bmcl.2006.11.067

Target ChEMBL ID: CHEMBL1795135
ChEMBL Target Name: 3-oxoacyl-[acyl-carrier-protein] synthase 3
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
100IC50>100000nM
100IC50>100000nM
100IC50>100000nM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Plasmodium falciparum
External ID: CHEMBL891692
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem. Lett.
Year: 2007
Volume: 17
Issue: 4
First Page: 879
Last Page: 883
DOI: 10.1016/j.bmcl.2006.11.067

Target ChEMBL ID: CHEMBL364
ChEMBL Target Name: Plasmodium falciparum
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
55.5IC50=55500nM
100IC50>100000nM
100IC50>100000nM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:3-oxoacyl-[acyl-carrier-protein] synthase 3
External ID: CHEMBL891695
Protocol: N/A
Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2007
Volume: 17
Issue: 4
First Page: 879
Last Page: 883
DOI: 10.1016/j.bmcl.2006.11.067

Target ChEMBL ID: CHEMBL3640
ChEMBL Target Name: 3-oxoacyl-[acyl-carrier-protein] synthase III
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned
Standard TypeActivity Comment
ActivityNot Active
ActivityNot Active
ActivityNot Active
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Escherichia coli
External ID: CHEMBL891696
Protocol: N/A
Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2007
Volume: 17
Issue: 4
First Page: 879
Last Page: 883
DOI: 10.1016/j.bmcl.2006.11.067

Target ChEMBL ID: CHEMBL354
ChEMBL Target Name: Escherichia coli
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
MIC=6.6ug.mL-1