HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Prostaglandin G/H synthase 1

External ID: CHEMBL760771

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1990
Volume: 33
Issue: 7
First Page: 2019
Last Page: 2024
DOI: 10.1021/jm00169a035

Target ChEMBL ID: CHEMBL2095157
ChEMBL Target Name: Cyclooxygenase
ChEMBL Target Type: PROTEIN FAMILY - Target is a group of closely related proteins
Relationship Type: H - Homologous protein target assigned
Confidence: Multiple homologous protein targets may be assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
100	IC50	>	100000	nM
3.5	IC50	=	3500	nM
30	IC50	=	30000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Polyunsaturated fatty acid 5-lipoxygenase

External ID: CHEMBL619928

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1990
Volume: 33
Issue: 7
First Page: 2019
Last Page: 2024
DOI: 10.1021/jm00169a035

Target ChEMBL ID: CHEMBL312
ChEMBL Target Name: Arachidonate 5-lipoxygenase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
24	IC50	=	24000	nM
1.4	IC50	=	1400	nM
18	IC50	=	18000	nM
0.02	IC50	=	20	nM
9	IC50	=	9000	nM

92-81-9 靶点实验数据