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899357-78-9 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:INS1
External ID: CHEMBL3802535
Protocol: N/A
Comment: Journal: Bioorg. Med. Chem.
Year: 2016
Volume: 24
Issue: 12
First Page: 2621
Last Page: 2630
DOI: 10.1016/j.bmc.2016.03.057

Target ChEMBL ID: CHEMBL613545
ChEMBL Target Name: INS1
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
%max=12%
%max=87%
%max=81%
%max=92%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:INS1
External ID: CHEMBL3802538
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem.
Year: 2016
Volume: 24
Issue: 12
First Page: 2621
Last Page: 2630
DOI: 10.1016/j.bmc.2016.03.057

Target ChEMBL ID: CHEMBL613545
ChEMBL Target Name: INS1
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard UnitsActivity Comment
1.3EC50=1300nM
ActivityDose-dependent effect
3.2EC50=3200nM
3.5EC50=3500nM
9EC50=9000nM
1.6EC50=1600nM
5.8EC50=5800nM
1EC50=1000nM
7.8EC50=7800nM
1.7EC50=1700nM
3.2EC50=3200nM
2.8EC50=2800nM
8EC50=8000nM
3.1EC50=3100nM
2.6EC50=2600nM
6.5EC50=6500nM
8.7EC50=8700nM
2.8EC50=2800nM