HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Enterococcus faecalis

External ID: CHEMBL812168

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1989
Volume: 32
Issue: 8
First Page: 1936
Last Page: 1942
DOI: 10.1021/jm00128a041

Target ChEMBL ID: CHEMBL362
ChEMBL Target Name: Enterococcus faecalis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	3	ug.mL-1
MIC	=	1	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Citrobacter freundii

External ID: CHEMBL658723

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1989
Volume: 32
Issue: 8
First Page: 1936
Last Page: 1942
DOI: 10.1021/jm00128a041

Target ChEMBL ID: CHEMBL612615
ChEMBL Target Name: Citrobacter freundii
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	100	ug.mL-1
MIC	=	3	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Salmonella enterica subsp. enterica serovar Typhimurium

External ID: CHEMBL805697

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1989
Volume: 32
Issue: 8
First Page: 1936
Last Page: 1942
DOI: 10.1021/jm00128a041

Target ChEMBL ID: CHEMBL351
ChEMBL Target Name: Salmonella typhimurium
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	100	ug.mL-1
MIC	=	3	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Escherichia coli

External ID: CHEMBL673738

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1989
Volume: 32
Issue: 8
First Page: 1936
Last Page: 1942
DOI: 10.1021/jm00128a041

Target ChEMBL ID: CHEMBL354
ChEMBL Target Name: Escherichia coli
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	300	ug.mL-1
MIC	=	3	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Dihydrofolate reductase

External ID: CHEMBL668125

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1989
Volume: 32
Issue: 8
First Page: 1936
Last Page: 1942
DOI: 10.1021/jm00128a041

Target ChEMBL ID: CHEMBL1809
ChEMBL Target Name: Dihydrofolate reductase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
0.0052	IC50	=	5.2	nM
0.033	IC50	=	33	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Proteus vulgaris

External ID: CHEMBL771769

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1989
Volume: 32
Issue: 8
First Page: 1936
Last Page: 1942
DOI: 10.1021/jm00128a041

Target ChEMBL ID: CHEMBL614450
ChEMBL Target Name: Proteus vulgaris
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	30	ug.mL-1
MIC	=	3	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Serratia marcescens

External ID: CHEMBL805409

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1989
Volume: 32
Issue: 8
First Page: 1936
Last Page: 1942
DOI: 10.1021/jm00128a041

Target ChEMBL ID: CHEMBL614593
ChEMBL Target Name: Serratia marcescens
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	>	100	ug.mL-1
MIC	=	3	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Staphylococcus aureus

External ID: CHEMBL811171

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1989
Volume: 32
Issue: 8
First Page: 1936
Last Page: 1942
DOI: 10.1021/jm00128a041

Target ChEMBL ID: CHEMBL352
ChEMBL Target Name: Staphylococcus aureus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	10	ug.mL-1
MIC	=	0.3	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Streptococcus agalactiae

External ID: CHEMBL813308

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1989
Volume: 32
Issue: 8
First Page: 1936
Last Page: 1942
DOI: 10.1021/jm00128a041

Target ChEMBL ID: CHEMBL614622
ChEMBL Target Name: Streptococcus agalactiae
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	3	ug.mL-1
MIC	=	1	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Dihydrofolate reductase

External ID: CHEMBL667224

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1989
Volume: 32
Issue: 8
First Page: 1936
Last Page: 1942
DOI: 10.1021/jm00128a041

Target ChEMBL ID: CHEMBL2363
ChEMBL Target Name: Dihydrofolate reductase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
62	IC50	=	62000	nM
70	IC50	=	70000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Vibrio cholerae

External ID: CHEMBL816178

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1989
Volume: 32
Issue: 8
First Page: 1936
Last Page: 1942
DOI: 10.1021/jm00128a041

Target ChEMBL ID: CHEMBL614402
ChEMBL Target Name: Vibrio cholerae
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	3	ug.mL-1
MIC	=	1	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Dihydrofolate reductase

External ID: CHEMBL667603

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1989
Volume: 32
Issue: 8
First Page: 1936
Last Page: 1942
DOI: 10.1021/jm00128a041

Target ChEMBL ID: CHEMBL202
ChEMBL Target Name: Dihydrofolate reductase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
1.8	IC50	=	1800	nM
0.14	IC50	=	140	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Klebsiella pneumoniae

External ID: CHEMBL704222

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1989
Volume: 32
Issue: 8
First Page: 1936
Last Page: 1942
DOI: 10.1021/jm00128a041

Target ChEMBL ID: CHEMBL350
ChEMBL Target Name: Klebsiella pneumoniae
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	100	ug.mL-1
MIC	=	10	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Streptococcus pyogenes

External ID: CHEMBL808428

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1989
Volume: 32
Issue: 8
First Page: 1936
Last Page: 1942
DOI: 10.1021/jm00128a041

Target ChEMBL ID: CHEMBL356
ChEMBL Target Name: Streptococcus pyogenes
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	3	ug.mL-1
MIC	=	0.3	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Klebsiella aerogenes

External ID: CHEMBL677683

Protocol: N/A

Comment: Journal: J Med Chem
Year: 1989
Volume: 32
Issue: 8
First Page: 1936
Last Page: 1942
DOI: 10.1021/jm00128a041

Target ChEMBL ID: CHEMBL612508
ChEMBL Target Name: Klebsiella aerogenes
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	300	ug.mL-1
MIC	=	10	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Pasteurella multocida

External ID: CHEMBL764528

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1989
Volume: 32
Issue: 8
First Page: 1936
Last Page: 1942
DOI: 10.1021/jm00128a041

Target ChEMBL ID: CHEMBL614409
ChEMBL Target Name: Pasteurella multocida
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	10	ug.mL-1
MIC	=	3	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mycolicibacterium smegmatis

External ID: CHEMBL749709

Protocol: N/A

Comment: Journal: J Med Chem
Year: 1989
Volume: 32
Issue: 8
First Page: 1936
Last Page: 1942
DOI: 10.1021/jm00128a041

Target ChEMBL ID: CHEMBL613088
ChEMBL Target Name: Mycolicibacterium smegmatis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	3	ug.mL-1
MIC	=	3	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Shigella flexneri

External ID: CHEMBL802299

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1989
Volume: 32
Issue: 8
First Page: 1936
Last Page: 1942
DOI: 10.1021/jm00128a041

Target ChEMBL ID: CHEMBL614396
ChEMBL Target Name: Shigella flexneri
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	300	ug.mL-1
MIC	=	3	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Bordetella bronchiseptica

External ID: CHEMBL652890

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1989
Volume: 32
Issue: 8
First Page: 1936
Last Page: 1942
DOI: 10.1021/jm00128a041

Target ChEMBL ID: CHEMBL612286
ChEMBL Target Name: Bordetella bronchiseptica
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	>	100	ug.mL-1
MIC	=	10	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Proteus mirabilis

External ID: CHEMBL764052

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1989
Volume: 32
Issue: 8
First Page: 1936
Last Page: 1942
DOI: 10.1021/jm00128a041

Target ChEMBL ID: CHEMBL614444
ChEMBL Target Name: Proteus mirabilis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	30	ug.mL-1
MIC	=	10	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL796195

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1989
Volume: 32
Issue: 8
First Page: 1936
Last Page: 1942
DOI: 10.1021/jm00128a041

Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
MIC	=	1000	ug.mL-1
MIC	=	10	ug.mL-1

89446-56-0 靶点实验数据