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885271-95-4 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Fibroblast growth factor receptor 1
External ID: CHEMBL4136628
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: ACS Med Chem Lett
Year: 2017
Volume: 8
Issue: 12
First Page: 1264
Last Page: 1268
DOI: 10.1021/acsmedchemlett.7b00349

Target ChEMBL ID: CHEMBL3650
ChEMBL Target Name: Fibroblast growth factor receptor 1
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard UnitsActivity Comment
IC50Not Determined
14IC50=14000nM
83IC50=83000nM
IC50Not Determined
IC50Not Determined
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Fibroblast growth factor receptor 1
External ID: CHEMBL4136629
Protocol: N/A
Comment: Journal: ACS Med Chem Lett
Year: 2017
Volume: 8
Issue: 12
First Page: 1264
Last Page: 1268
DOI: 10.1021/acsmedchemlett.7b00349

Target ChEMBL ID: CHEMBL3650
ChEMBL Target Name: Fibroblast growth factor receptor 1
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned
Standard TypeStandard RelationStandard ValueStandard Units
Inhibition=20%
Inhibition=29%