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885271-88-5 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL4649948
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Data Source: Gates Foundation Compound Collection
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard UnitsData Validity Comment
Percent Effect=-0.4113%
Percent Effect=5.918%
Percent Effect=24.74%
Percent Effect=-17.79%
Percent Effect=76.74%
22.7813IC50=22781.31nM
Percent Effect=-1.838%
Percent Effect=13.25%
Percent Effect=8.892%
Percent Effect=-2.138%
Percent Effect=-11.1%
Percent Effect=12.13%
Percent Effect=5.305%
Percent Effect=4.955%
Percent Effect=21.13%
Percent Effect=2.237%
Percent Effect=8.675%
Percent Effect=-6.461%
Percent Effect=-6.594%
Percent Effect=-15.11%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL4649949
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Data Source: Gates Foundation Compound Collection
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard UnitsData Validity Comment
Percent Effect=-3.24%
Percent Effect=-13.31%
Percent Effect=-14.92%
Percent Effect=19.22%
Percent Effect=0.5922%
Percent Effect=5.491%
Percent Effect=16.44%
Percent Effect=-8.493%
Percent Effect=31.52%
Percent Effect=-34.04%
Percent Effect=15.71%
Percent Effect=7.437%
Percent Effect=1.274%
Percent Effect=47.08%
Percent Effect=-6.198%
Percent Effect=34.07%
Percent Effect=24.8%
Percent Effect=26.03%
Percent Effect=-7.513%
Percent Effect=20.66%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Acinetobacter baumannii
External ID: CHEMBL4296188
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL614425
ChEMBL Target Name: Acinetobacter baumannii
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Data Source: CO-ADD Antimicrobial Screening
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard UnitsActivity CommentData Validity Comment
10MIC>10000nMMedian N= 2; Maxinhib 10.4 Pct
20MIC>20000nMMedian N= 2; Maxinhib 10.3 Pct
5MIC=5000nMMedian N= 2
Inhibition=22.02%Average; N=2
10MIC>10000nMMedian N= 2; Maxinhib 7.2 Pct
Inhibition=0.29%Average; N=2
Inhibition=13.44%Average; N=2
Inhibition=15.75%Average; N=2
Inhibition=30.31%Average; N=2
20MIC>20000nMMedian N= 2; Maxinhib 19.9 Pct
10MIC>10000nMMedian N= 2; Maxinhib 13.5 Pct
Inhibition=12.68%Average; N=2
Inhibition=8.04%Average; N=2
Inhibition=21.28%Average; N=2
20MIC>20000nMMedian N= 2; Maxinhib 17.6 Pct
10MIC>10000nMMedian N= 2; Maxinhib 10.9 Pct
20MIC>20000nMMedian N= 2; Maxinhib 24.8 Pct
Inhibition=19.94%Average; N=2
10MIC>10000nMMedian N= 2; Maxinhib 15.2 Pct
Inhibition=19.7%Average; N=2
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Pseudomonas aeruginosa
External ID: CHEMBL4296187
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL348
ChEMBL Target Name: Pseudomonas aeruginosa
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Data Source: CO-ADD Antimicrobial Screening
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard UnitsActivity CommentData Validity Comment
Inhibition=10.84%Average; N=1
Inhibition=14.55%Average; N=1
Inhibition=-13.46%Average; N=1Outside typical range
Inhibition=21.47%Average; N=2
Inhibition=32.07%Average; N=1
Inhibition=2.27%Average; N=1
Inhibition=-21.74%Average; N=1Outside typical range
Inhibition=9.41%Average; N=1
Inhibition=19.34%Average; N=1
Inhibition=-25.08%Average; N=1Outside typical range
Inhibition=9.21%Average; N=4
Inhibition=15.98%Average; N=4
Inhibition=8.03%Average; N=1
Inhibition=-1.26%Average; N=1
Inhibition=6.81%Average; N=1
Inhibition=-8.48%Average; N=1
Inhibition=25.25%Average; N=1
Inhibition=44.67%Average; N=1
Inhibition=1.69%Average; N=1
Inhibition=2.93%Average; N=1
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Pseudomonas aeruginosa
External ID: CHEMBL4296802
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL348
ChEMBL Target Name: Pseudomonas aeruginosa
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Data Source: CO-ADD Antimicrobial Screening
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard UnitsActivity CommentData Validity Comment
Inhibition=-33.42%Average; N=1Outside typical range
Inhibition=1.44%Average; N=1
Inhibition=-11.05%Average; N=1Outside typical range
Inhibition=19.22%Average; N=1
Inhibition=-31.54%Average; N=1Outside typical range
Inhibition=-12.91%Average; N=1Outside typical range
Inhibition=12.18%Average; N=1
Inhibition=-14.83%Average; N=1Outside typical range
Inhibition=17.54%Average; N=1
Inhibition=-38.58%Average; N=1Outside typical range
Inhibition=-10.22%Average; N=1Outside typical range
Inhibition=14%Average; N=1
Inhibition=1.67%Average; N=1
Inhibition=14.76%Average; N=1
Inhibition=-28.2%Average; N=1Outside typical range
Inhibition=13.08%Average; N=1
Inhibition=3.75%Average; N=1
Inhibition=10.88%Average; N=1
Inhibition=-0.78%Average; N=1
Inhibition=-7.12%Average; N=1