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87367-63-3 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Mycobacterium avium subsp. paratuberculosis
External ID: CHEMBL2383539
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Eur. J. Med. Chem.
Year: 2013
Volume: 63
First Page: 731
Last Page: 738
DOI: 10.1016/j.ejmech.2013.03.023

Target ChEMBL ID: CHEMBL613087
ChEMBL Target Name: Mycobacterium avium subsp. paratuberculosis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
4.75MIC50=4750nM
10MIC50>10000nM
10MIC50>10000nM
5.05MIC50=5050nM
5.83MIC50=5830nM
4.23MIC50=4230nM
6.56MIC50=6560nM
10MIC50>10000nM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Mycobacterium ulcerans
External ID: CHEMBL2383538
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Eur. J. Med. Chem.
Year: 2013
Volume: 63
First Page: 731
Last Page: 738
DOI: 10.1016/j.ejmech.2013.03.023

Target ChEMBL ID: CHEMBL612965
ChEMBL Target Name: Mycobacterium ulcerans
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
8.21MIC50=8210nM
10MIC50>10000nM
10MIC50>10000nM
10MIC50>10000nM
10MIC50>10000nM
9.82MIC50=9820nM
10MIC50>10000nM
10MIC50>10000nM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL2383537
Protocol: N/A
Comment: Journal: Eur. J. Med. Chem.
Year: 2013
Volume: 63
First Page: 731
Last Page: 738
DOI: 10.1016/j.ejmech.2013.03.023
Standard TypeStandard RelationStandard Value
Ratio=5
Ratio=5
Ratio=5
Ratio=5
Ratio=5
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL2383536
Protocol: N/A
Comment: Journal: Eur. J. Med. Chem.
Year: 2013
Volume: 63
First Page: 731
Last Page: 738
DOI: 10.1016/j.ejmech.2013.03.023
Standard TypeStandard RelationStandard Value
Ratio=5
Ratio=5
Ratio=5
Ratio=5
Ratio=5
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Mycobacterium tuberculosis
External ID: CHEMBL2383542
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Eur J Med Chem
Year: 2013
Volume: 63
First Page: 731
Last Page: 738
DOI: 10.1016/j.ejmech.2013.03.023

Target ChEMBL ID: CHEMBL360
ChEMBL Target Name: Mycobacterium tuberculosis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
0.52MIC50=520nM
3MIC50=3000nM
2.65MIC50=2650nM
0.85MIC50=850nM
0.85MIC50=850nM
0.64MIC50=640nM
0.83MIC50=830nM
2.23MIC50=2230nM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Mycobacterium tuberculosis variant bovis
External ID: CHEMBL2383541
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Eur J Med Chem
Year: 2013
Volume: 63
First Page: 731
Last Page: 738
DOI: 10.1016/j.ejmech.2013.03.023

Target ChEMBL ID: CHEMBL613086
ChEMBL Target Name: Mycobacterium tuberculosis variant bovis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
0.64MIC50=640nM
2.93MIC50=2930nM
2.65MIC50=2650nM
0.97MIC50=970nM
0.95MIC50=950nM
0.71MIC50=710nM
0.94MIC50=940nM
2.41MIC50=2410nM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:NON-PROTEIN TARGET
External ID: CHEMBL2383540
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Eur. J. Med. Chem.
Year: 2013
Volume: 63
First Page: 731
Last Page: 738
DOI: 10.1016/j.ejmech.2013.03.023

Target ChEMBL ID: CHEMBL3879801
ChEMBL Target Name: NON-PROTEIN TARGET
ChEMBL Target Type: NON-MOLECULAR - Target has not been defined at a molecular level, only the non-molecular entity which is affected (e.g., organism, cell line etc)
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
5.01MIC50=5010nM
10MIC50>10000nM
10MIC50>10000nM
5.12MIC50=5120nM
5.36MIC50=5360nM
4.96MIC50=4960nM
6.18MIC50=6180nM
10MIC50>10000nM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL2383531
Protocol: N/A
Comment: Journal: Eur. J. Med. Chem.
Year: 2013
Volume: 63
First Page: 731
Last Page: 738
DOI: 10.1016/j.ejmech.2013.03.023
Standard TypeStandard RelationStandard ValueStandard Units
Activity=90.4%
Activity=97.7%
Activity=96.8%
Activity=94.9%
Activity=100.2%
Activity=100.4%
Activity=97.9%
Activity=93.4%
Activity=93.6%
Activity=86.1%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL2383530
Protocol: N/A
Comment: Journal: Eur. J. Med. Chem.
Year: 2013
Volume: 63
First Page: 731
Last Page: 738
DOI: 10.1016/j.ejmech.2013.03.023
Standard TypeStandard RelationStandard ValueStandard Units
Activity=72.6%
Activity=96.6%
Activity=91.6%
Activity=94.8%
Activity=93%
Activity=78.9%
Activity=95.3%
Activity=85.9%
Activity=85%
Activity=73.2%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL2383529
Protocol: N/A
Comment: Journal: Eur. J. Med. Chem.
Year: 2013
Volume: 63
First Page: 731
Last Page: 738
DOI: 10.1016/j.ejmech.2013.03.023
Standard TypeStandard RelationStandard ValueStandard Units
Activity=45.6%
Activity=72.8%
Activity=78.6%
Activity=77.4%
Activity=75.7%
Activity=53.4%
Activity=69%
Activity=59.3%
Activity=70.5%
Activity=55.7%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Salmonella enterica subsp. enterica serovar Typhimurium
External ID: CHEMBL2383528
Protocol: N/A
Comment: Journal: Eur. J. Med. Chem.
Year: 2013
Volume: 63
First Page: 731
Last Page: 738
DOI: 10.1016/j.ejmech.2013.03.023

Target ChEMBL ID: CHEMBL351
ChEMBL Target Name: Salmonella typhimurium
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
10Activity>10uM
10Activity>10uM
10Activity>10uM
10Activity>10uM
10Activity>10uM
10Activity>10uM
10Activity>10uM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL2383535
Protocol: N/A
Comment: Journal: Eur. J. Med. Chem.
Year: 2013
Volume: 63
First Page: 731
Last Page: 738
DOI: 10.1016/j.ejmech.2013.03.023
Standard TypeStandard RelationStandard Value
Selectivity Index>110.4
Selectivity Index>233.8
Selectivity Index>60
Selectivity Index>67.9
Selectivity Index>189.5
Selectivity Index>211.8
Selectivity Index>211.8
Selectivity Index>216.9
Selectivity Index>80.7
Selectivity Index>56.1
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Mycobacterium tuberculosis
External ID: CHEMBL2383534
Protocol: N/A
Comment: Journal: Eur J Med Chem
Year: 2013
Volume: 63
First Page: 731
Last Page: 738
DOI: 10.1016/j.ejmech.2013.03.023

Target ChEMBL ID: CHEMBL360
ChEMBL Target Name: Mycobacterium tuberculosis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
GI=97.7%
GI=46.8%
GI=60.9%
GI=41.3%
GI=42%
GI=62.1%
GI=55%
GI=58.7%
GI=52.6%
GI=39.2%
GI=41.3%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Mycobacterium tuberculosis
External ID: CHEMBL2383533
Protocol: N/A
Comment: Journal: Eur J Med Chem
Year: 2013
Volume: 63
First Page: 731
Last Page: 738
DOI: 10.1016/j.ejmech.2013.03.023

Target ChEMBL ID: CHEMBL360
ChEMBL Target Name: Mycobacterium tuberculosis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
GI=82.3%
GI=38.1%
GI=39.6%
GI=35.2%
GI=29.9%
GI=45.7%
GI=43.3%
GI=42.9%
GI=46.6%
GI=32.6%
GI=39%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Mycobacterium tuberculosis
External ID: CHEMBL2383532
Protocol: N/A
Comment: Journal: Eur J Med Chem
Year: 2013
Volume: 63
First Page: 731
Last Page: 738
DOI: 10.1016/j.ejmech.2013.03.023

Target ChEMBL ID: CHEMBL360
ChEMBL Target Name: Mycobacterium tuberculosis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
GI=37%
GI=0.2%
GI=11.1%
GI=1.6%
GI=-1.2%
GI=-0.5%
GI=-1.2%
GI=0.6%
GI=3.2%
GI=0.3%
GI=-0.9%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Salmonella enterica subsp. enterica serovar Typhimurium
External ID: CHEMBL2383448
Protocol: N/A
Comment: Journal: Eur. J. Med. Chem.
Year: 2013
Volume: 63
First Page: 731
Last Page: 738
DOI: 10.1016/j.ejmech.2013.03.023

Target ChEMBL ID: CHEMBL351
ChEMBL Target Name: Salmonella typhimurium
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
10Activity>10uM
10Activity>10uM
10Activity>10uM
10Activity>10uM
10Activity>10uM
10Activity>10uM
10Activity>10uM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Salmonella enterica subsp. enterica serovar Typhimurium
External ID: CHEMBL2383447
Protocol: N/A
Comment: Journal: Eur. J. Med. Chem.
Year: 2013
Volume: 63
First Page: 731
Last Page: 738
DOI: 10.1016/j.ejmech.2013.03.023

Target ChEMBL ID: CHEMBL351
ChEMBL Target Name: Salmonella typhimurium
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
10Activity>10uM
10Activity>10uM
10Activity>10uM
10Activity>10uM
10Activity>10uM
10Activity>10uM
10Activity>10uM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Salmonella enterica subsp. enterica serovar Typhimurium
External ID: CHEMBL2383446
Protocol: N/A
Comment: Journal: Eur. J. Med. Chem.
Year: 2013
Volume: 63
First Page: 731
Last Page: 738
DOI: 10.1016/j.ejmech.2013.03.023

Target ChEMBL ID: CHEMBL351
ChEMBL Target Name: Salmonella typhimurium
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
10Activity>10uM
10Activity>10uM
10Activity>10uM
10Activity>10uM
10Activity>10uM
10Activity>10uM
10Activity>10uM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Mycobacterium tuberculosis
External ID: CHEMBL2384292
Protocol: N/A
Comment: Journal: Eur J Med Chem
Year: 2013
Volume: 63
First Page: 731
Last Page: 738
DOI: 10.1016/j.ejmech.2013.03.023

Target ChEMBL ID: CHEMBL360
ChEMBL Target Name: Mycobacterium tuberculosis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
GI=100%
GI=27%
GI=39%
GI=95%
GI=100%
GI=85%
GI=84%
GI=98%
GI=97%
GI=70%
GI=99%
GI=99%
GI=40%
GI=99%
GI=40%
GI=39%
GI=17%
GI=90%
GI=87%
GI<10%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Mycobacterium tuberculosis
External ID: CHEMBL2383546
Protocol: N/A
Comment: Journal: Eur J Med Chem
Year: 2013
Volume: 63
First Page: 731
Last Page: 738
DOI: 10.1016/j.ejmech.2013.03.023

Target ChEMBL ID: CHEMBL360
ChEMBL Target Name: Mycobacterium tuberculosis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
GI=100%
GI=30%
GI=15%
GI=39%
GI=71%
GI=30%
GI=35%
GI=59%
GI<10%
GI=12%
GI=62%
GI=64%
GI<10%
GI=65%
GI<10%
GI=26%
GI=17%
GI=41%
GI=25%
GI<10%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Mycobacterium tuberculosis
External ID: CHEMBL2383545
Protocol: N/A
Comment: Journal: Eur J Med Chem
Year: 2013
Volume: 63
First Page: 731
Last Page: 738
DOI: 10.1016/j.ejmech.2013.03.023

Target ChEMBL ID: CHEMBL360
ChEMBL Target Name: Mycobacterium tuberculosis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
GI=98%
GI<10%
GI<10%
GI<10%
GI=20%
GI<10%
GI<10%
GI=11%
GI<10%
GI<10%
GI=13%
GI=13%
GI<10%
GI=15%
GI<10%
GI<10%
GI<10%
GI<10%
GI<10%
GI<10%