HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL1936224

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Eur. J. Med. Chem.
Year: 2012
Volume: 48
First Page: 97
Last Page: 107
DOI: 10.1016/j.ejmech.2011.11.039

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
0.18	Ki	=	180	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：D(2) dopamine receptor

External ID: CHEMBL4709829

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 207
First Page: 112709
Last Page: 112709
DOI: 10.1016/j.ejmech.2020.112709

Target ChEMBL ID: CHEMBL217
ChEMBL Target Name: Dopamine D2 receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Standard Type	Standard Relation	Standard Value	Standard Units
Inhibition	=	100.1	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL1815886

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 2011
Volume: 54
Issue: 15
First Page: 5508
Last Page: 5521
DOI: 10.1021/jm200334c

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
5.0E-4	Ki	=	0.5	nM
0.27	Ki	=	270	nM
10	Ki	>	10000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL1815888

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 2011
Volume: 54
Issue: 15
First Page: 5508
Last Page: 5521
DOI: 10.1021/jm200334c

Standard Type	Standard Relation	Standard Value	Activity Comment
Ratio Ki			Not Determined
Ratio Ki	=	12
Ratio Ki			Not Determined

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL1815887

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 2011
Volume: 54
Issue: 15
First Page: 5508
Last Page: 5521
DOI: 10.1021/jm200334c

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
	Ki				Not Determined
5.53	Ki	=	5530	nM
7.38	Ki	=	7380	nM

87134-87-0 靶点实验数据