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86471-13-8 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Cricetinae gen. sp.
External ID: CHEMBL692451
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 1983
Volume: 26
Issue: 11
First Page: 1653
Last Page: 1656
DOI: 10.1021/jm00365a021

Target ChEMBL ID: CHEMBL612361
ChEMBL Target Name: Cricetinae gen. sp.
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
Active culture=11%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Cricetinae gen. sp.
External ID: CHEMBL693648
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 1983
Volume: 26
Issue: 11
First Page: 1653
Last Page: 1656
DOI: 10.1021/jm00365a021

Target ChEMBL ID: CHEMBL612361
ChEMBL Target Name: Cricetinae gen. sp.
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
Active culture=7%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Ornithine decarboxylase
External ID: CHEMBL753501
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 1983
Volume: 26
Issue: 11
First Page: 1653
Last Page: 1656
DOI: 10.1021/jm00365a021

Target ChEMBL ID: CHEMBL2840
ChEMBL Target Name: Ornithine decarboxylase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned
Standard TypeStandard RelationStandard ValueStandard Units
Inhibition=80%
Inhibition=48%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Ornithine decarboxylase
External ID: CHEMBL753500
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 1983
Volume: 26
Issue: 11
First Page: 1653
Last Page: 1656
DOI: 10.1021/jm00365a021

Target ChEMBL ID: CHEMBL2840
ChEMBL Target Name: Ornithine decarboxylase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned
Standard TypeStandard RelationStandard ValueStandard Units
Inhibition=56%
Inhibition=30%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Cricetinae gen. sp.
External ID: CHEMBL692484
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 1983
Volume: 26
Issue: 11
First Page: 1653
Last Page: 1656
DOI: 10.1021/jm00365a021

Target ChEMBL ID: CHEMBL612361
ChEMBL Target Name: Cricetinae gen. sp.
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
Active culture=6%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Cricetinae gen. sp.
External ID: CHEMBL692487
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 1983
Volume: 26
Issue: 11
First Page: 1653
Last Page: 1656
DOI: 10.1021/jm00365a021

Target ChEMBL ID: CHEMBL612361
ChEMBL Target Name: Cricetinae gen. sp.
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
Active culture=1%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Ornithine decarboxylase
External ID: CHEMBL756687
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 1984
Volume: 27
Issue: 11
First Page: 1516
Last Page: 1531
DOI: 10.1021/jm00377a022

Target ChEMBL ID: CHEMBL2840
ChEMBL Target Name: Ornithine decarboxylase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned
Standard TypeStandard RelationStandard ValueStandard Units
Inhibition=33%
Inhibition=30%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Cricetinae gen. sp.
External ID: CHEMBL690441
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 1984
Volume: 27
Issue: 11
First Page: 1516
Last Page: 1531
DOI: 10.1021/jm00377a022

Target ChEMBL ID: CHEMBL612361
ChEMBL Target Name: Cricetinae gen. sp.
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
Activity=7%
Activity=7%
Activity=7%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Ornithine decarboxylase
External ID: CHEMBL755844
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 1984
Volume: 27
Issue: 11
First Page: 1516
Last Page: 1531
DOI: 10.1021/jm00377a022

Target ChEMBL ID: CHEMBL2840
ChEMBL Target Name: Ornithine decarboxylase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned
Standard TypeStandard RelationStandard ValueStandard Units
Inhibition=56%
Inhibition=48%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Cricetinae gen. sp.
External ID: CHEMBL689376
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 1984
Volume: 27
Issue: 11
First Page: 1516
Last Page: 1531
DOI: 10.1021/jm00377a022

Target ChEMBL ID: CHEMBL612361
ChEMBL Target Name: Cricetinae gen. sp.
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
Activity=6%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Cricetinae gen. sp.
External ID: CHEMBL690255
Protocol: N/A
Comment: Journal: J Med Chem
Year: 1984
Volume: 27
Issue: 11
First Page: 1516
Last Page: 1531
DOI: 10.1021/jm00377a022

Target ChEMBL ID: CHEMBL612361
ChEMBL Target Name: Cricetinae gen. sp.
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard Value
ED50=0
ED50=0
ED50=0
ED50=0
ED50=0
ED50=0
ED50=0
ED50>1.0E-8
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Cricetinae gen. sp.
External ID: CHEMBL689378
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 1984
Volume: 27
Issue: 11
First Page: 1516
Last Page: 1531
DOI: 10.1021/jm00377a022

Target ChEMBL ID: CHEMBL612361
ChEMBL Target Name: Cricetinae gen. sp.
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
Activity=1%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Cricetinae gen. sp.
External ID: CHEMBL689824
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 1984
Volume: 27
Issue: 11
First Page: 1516
Last Page: 1531
DOI: 10.1021/jm00377a022

Target ChEMBL ID: CHEMBL612361
ChEMBL Target Name: Cricetinae gen. sp.
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
Activity=11%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL852217
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 1983
Volume: 26
Issue: 11
First Page: 1653
Last Page: 1656
DOI: 10.1021/jm00365a021
Standard TypeStandard RelationStandard Value
Ratio=0.4