HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：HepG2-CD81

External ID: CHEMBL4483864

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Science
Year: 2018
Volume: 362
Issue: 6419
DOI: 10.1126/science.aat9446

Target ChEMBL ID: CHEMBL4543887
ChEMBL Target Name: HepG2-CD81
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Data Source: Winzeler Lab Plasmodium Screening

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
3.48	HEPG2TOX ASSAY - CC90	=	3.48	uM
1.05	HEPG2TOX ASSAY - CC50	=	1.05	uM
1.05	HEPG2TOX ASSAY - CC90	=	1.05	uM
6.54	HEPG2TOX ASSAY - CC50	=	6.54	uM
4.75	HEPG2TOX ASSAY - CC90	=	4.75	uM
1.63	HEPG2TOX ASSAY - CC50	=	1.63	uM
1.63	HEPG2TOX ASSAY - CC90	=	1.63	uM
7.48	HEPG2TOX ASSAY - CC50	=	7.48	uM
3.26	HEPG2TOX ASSAY - CC90	=	3.26	uM
0.0189	HEPG2TOX ASSAY - CC50	=	0.0189	uM
6.77	HEPG2TOX ASSAY - CC90	=	6.77	uM
7.54	HEPG2TOX ASSAY - CC50	=	7.54	uM
12.4	HEPG2TOX ASSAY - CC90	>	12.4	uM
6.3	HEPG2TOX ASSAY - CC50	=	6.3	uM
6.3	HEPG2TOX ASSAY - CC90	=	6.3	uM
9.05	HEPG2TOX ASSAY - CC50	=	9.05	uM
14.9	HEPG2TOX ASSAY - CC90	>	14.9	uM
12.7	HEPG2TOX ASSAY - CC50	>	12.7	uM
12.7	HEPG2TOX ASSAY - CC90	>	12.7	uM
8.37	HEPG2TOX ASSAY - CC50	>	8.37	uM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Plasmodium berghei

External ID: CHEMBL4483863

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Science
Year: 2018
Volume: 362
Issue: 6419
DOI: 10.1126/science.aat9446

Target ChEMBL ID: CHEMBL612653
ChEMBL Target Name: Plasmodium berghei
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Data Source: Winzeler Lab Plasmodium Screening

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
9.56	LUCIFERASE EXPRESSION CONTROL - IC90	>	9.56	uM
1.17	LUCIFERASE INFECTION ASSAY - IC50	=	1.17	uM
1.41	LUCIFERASE INFECTION ASSAY - IC90	=	1.41	uM
10	LUCIFERASE EXPRESSION CONTROL - IC50	>	10	uM
9.72	LUCIFERASE EXPRESSION CONTROL - IC90	>	9.72	uM
9.01	LUCIFERASE INFECTION ASSAY - IC50	>	9.01	uM
9.01	LUCIFERASE INFECTION ASSAY - IC90	>	9.01	uM
9.01	LUCIFERASE EXPRESSION CONTROL - IC50	>	9.01	uM
9.01	LUCIFERASE EXPRESSION CONTROL - IC90	>	9.01	uM
8.99	LUCIFERASE INFECTION ASSAY - IC50	=	8.99	uM
10	LUCIFERASE INFECTION ASSAY - IC90	>	10	uM
10	LUCIFERASE EXPRESSION CONTROL - IC50	>	10	uM
9.81	LUCIFERASE EXPRESSION CONTROL - IC90	>	9.81	uM
3.23	LUCIFERASE INFECTION ASSAY - IC50	=	3.23	uM
6.33	LUCIFERASE INFECTION ASSAY - IC90	>	6.33	uM
6.33	LUCIFERASE EXPRESSION CONTROL - IC50	>	6.33	uM
8.74	LUCIFERASE EXPRESSION CONTROL - IC90	>	8.74	uM
10	LUCIFERASE INFECTION ASSAY - IC50	>	10	uM
10	LUCIFERASE INFECTION ASSAY - IC90	>	10	uM
10	LUCIFERASE EXPRESSION CONTROL - IC50	>	10	uM

856005-97-5 靶点实验数据