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85597-17-7 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Enterococcus faecium
External ID: CHEMBL811836
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 1986
Volume: 29
Issue: 6
First Page: 1080
Last Page: 1087
DOI: 10.1021/jm00156a029

Target ChEMBL ID: CHEMBL357
ChEMBL Target Name: Enterococcus faecium
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
IC50=0.049ug.mL-1
IC50=3ug.mL-1
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Lacticaseibacillus casei
External ID: CHEMBL705374
Protocol: N/A
Comment: Journal: J Med Chem
Year: 1986
Volume: 29
Issue: 6
First Page: 1080
Last Page: 1087
DOI: 10.1021/jm00156a029

Target ChEMBL ID: CHEMBL613075
ChEMBL Target Name: Lacticaseibacillus casei
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard UnitsData Validity Comment
IC50=3.5ug.mL-1
IC50>500ug.mL-1Outside typical range
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Enterococcus faecium
External ID: CHEMBL816660
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 1986
Volume: 29
Issue: 6
First Page: 1080
Last Page: 1087
DOI: 10.1021/jm00156a029

Target ChEMBL ID: CHEMBL357
ChEMBL Target Name: Enterococcus faecium
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
IC50=9.0E-5ug.mL-1
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Lacticaseibacillus casei
External ID: CHEMBL707221
Protocol: N/A
Comment: Journal: J Med Chem
Year: 1986
Volume: 29
Issue: 6
First Page: 1080
Last Page: 1087
DOI: 10.1021/jm00156a029

Target ChEMBL ID: CHEMBL613075
ChEMBL Target Name: Lacticaseibacillus casei
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
IC50=5.4E-5ug.mL-1
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Thymidylate synthase
External ID: CHEMBL813847
Protocol: N/A
Comment: Journal: J Med Chem
Year: 1986
Volume: 29
Issue: 6
First Page: 1080
Last Page: 1087
DOI: 10.1021/jm00156a029

Target ChEMBL ID: CHEMBL5328
ChEMBL Target Name: Thymidylate synthase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned
Standard TypeStandard RelationStandard ValueStandard Units
IC50=0.0017ug.mL-1
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Dihydrofolate reductase
External ID: CHEMBL666943
Protocol: N/A
Comment: Journal: J Med Chem
Year: 1986
Volume: 29
Issue: 6
First Page: 1080
Last Page: 1087
DOI: 10.1021/jm00156a029

Target ChEMBL ID: CHEMBL2902
ChEMBL Target Name: Dihydrofolate reductase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned
Standard TypeStandard RelationStandard ValueStandard Units
IC50=0.007ug.mL-1