HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：PBMC

External ID: CHEMBL995735

Protocol: N/A

Comment: Journal: J. Nat. Prod.
Year: 2004
Volume: 67
Issue: 11
First Page: 1919
Last Page: 1924
DOI: 10.1021/np040006s

Target ChEMBL ID: CHEMBL613107
ChEMBL Target Name: PBMC
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：PBMC

External ID: CHEMBL995734

Protocol: N/A

Comment: Journal: J. Nat. Prod.
Year: 2004
Volume: 67
Issue: 11
First Page: 1919
Last Page: 1924
DOI: 10.1021/np040006s

Target ChEMBL ID: CHEMBL613107
ChEMBL Target Name: PBMC
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：PBMC

External ID: CHEMBL995736

Protocol: N/A

Comment: Journal: J. Nat. Prod.
Year: 2004
Volume: 67
Issue: 11
First Page: 1919
Last Page: 1924
DOI: 10.1021/np040006s

Target ChEMBL ID: CHEMBL613107
ChEMBL Target Name: PBMC
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：PBMC

External ID: CHEMBL995731

Protocol: N/A

Comment: Journal: J. Nat. Prod.
Year: 2004
Volume: 67
Issue: 11
First Page: 1919
Last Page: 1924
DOI: 10.1021/np040006s

Target ChEMBL ID: CHEMBL613107
ChEMBL Target Name: PBMC
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：PBMC

External ID: CHEMBL995730

Protocol: N/A

Comment: Journal: J. Nat. Prod.
Year: 2004
Volume: 67
Issue: 11
First Page: 1919
Last Page: 1924
DOI: 10.1021/np040006s

Target ChEMBL ID: CHEMBL613107
ChEMBL Target Name: PBMC
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	<	7.8	pg/ml
Activity	<	7.8	pg/ml
Activity	=	24.6	pg/ml
Activity	<	7.8	pg/ml
Activity	=	322.9	pg/ml
Activity	<	7.8	pg/ml
Activity	<	7.8	pg/ml
Activity	<	7.8	pg/ml
Activity	<	7.8	pg/ml
Activity	<	7.8	pg/ml
Activity	<	7.8	pg/ml
Activity	<	7.8	pg/ml
Activity	<	7.8	pg/ml
Activity	<	7.8	pg/ml

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：PBMC

External ID: CHEMBL995733

Protocol: N/A

Comment: Journal: J. Nat. Prod.
Year: 2004
Volume: 67
Issue: 11
First Page: 1919
Last Page: 1924
DOI: 10.1021/np040006s

Target ChEMBL ID: CHEMBL613107
ChEMBL Target Name: PBMC
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：PBMC

External ID: CHEMBL995732

Protocol: N/A

Comment: Journal: J. Nat. Prod.
Year: 2004
Volume: 67
Issue: 11
First Page: 1919
Last Page: 1924
DOI: 10.1021/np040006s

Target ChEMBL ID: CHEMBL613107
ChEMBL Target Name: PBMC
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active
Activity	Not Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：A2780

External ID: CHEMBL5608929

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg Med Chem
Year: 2024
Volume: 110
First Page: 117788
Last Page: 117788
DOI: 10.1016/j.bmc.2024.117788

Target ChEMBL ID: CHEMBL614004
ChEMBL Target Name: A2780
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
3.932	IC50	=	3932	nM
60	IC50	>	60000	nM
60	IC50	>	60000	nM
60	IC50	>	60000	nM
60	IC50	>	60000	nM
60	IC50	>	60000	nM
60	IC50	>	60000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：PBMC

External ID: CHEMBL995727

Protocol: N/A

Comment: Journal: J. Nat. Prod.
Year: 2004
Volume: 67
Issue: 11
First Page: 1919
Last Page: 1924
DOI: 10.1021/np040006s

Target ChEMBL ID: CHEMBL613107
ChEMBL Target Name: PBMC
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	<	7.8	pg/ml
Activity	<	7.8	pg/ml
Activity	=	14.3	pg/ml
Activity	<	7.8	pg/ml
Activity	=	47.3	pg/ml
Activity	<	7.8	pg/ml
Activity	<	7.8	pg/ml
Activity	=	14.3	pg/ml
Activity	<	7.8	pg/ml
Activity	<	7.8	pg/ml
Activity	<	7.8	pg/ml
Activity	<	7.8	pg/ml
Activity	<	7.8	pg/ml
Activity	<	7.8	pg/ml

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：PBMC

External ID: CHEMBL995726

Protocol: N/A

Comment: Journal: J. Nat. Prod.
Year: 2004
Volume: 67
Issue: 11
First Page: 1919
Last Page: 1924
DOI: 10.1021/np040006s

Target ChEMBL ID: CHEMBL613107
ChEMBL Target Name: PBMC
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	175.5	pg/ml
Activity	=	76.1	pg/ml
Activity	=	1576.2	pg/ml
Activity	=	1454.4	pg/ml
Activity	=	2579.2	pg/ml
Activity	=	451.1	pg/ml
Activity	=	308.4	pg/ml
Activity	=	203.4	pg/ml
Activity	=	10.6	pg/ml
Activity	<	7.8	pg/ml
Activity	=	662.9	pg/ml
Activity	=	198.6	pg/ml
Activity	=	174.4	pg/ml
Activity	=	16.2	pg/ml

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：PBMC

External ID: CHEMBL995729

Protocol: N/A

Comment: Journal: J. Nat. Prod.
Year: 2004
Volume: 67
Issue: 11
First Page: 1919
Last Page: 1924
DOI: 10.1021/np040006s

Target ChEMBL ID: CHEMBL613107
ChEMBL Target Name: PBMC
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	<	7.8	pg/ml
Activity	<	7.8	pg/ml
Activity	=	22	pg/ml
Activity	<	7.8	pg/ml
Activity	=	132.5	pg/ml
Activity	<	7.8	pg/ml
Activity	<	7.8	pg/ml
Activity	=	31.3	pg/ml
Activity	<	7.8	pg/ml
Activity	<	7.8	pg/ml
Activity	<	7.8	pg/ml
Activity	<	7.8	pg/ml
Activity	<	7.8	pg/ml
Activity	<	7.8	pg/ml

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：PBMC

External ID: CHEMBL995728

Protocol: N/A

Comment: Journal: J. Nat. Prod.
Year: 2004
Volume: 67
Issue: 11
First Page: 1919
Last Page: 1924
DOI: 10.1021/np040006s

Target ChEMBL ID: CHEMBL613107
ChEMBL Target Name: PBMC
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	<	7.8	pg/ml
Activity	<	7.8	pg/ml
Activity	=	14.7	pg/ml
Activity	<	7.8	pg/ml
Activity	=	104.3	pg/ml
Activity	<	7.8	pg/ml
Activity	<	7.8	pg/ml
Activity	<	7.8	pg/ml
Activity	<	7.8	pg/ml
Activity	<	7.8	pg/ml
Activity	<	7.8	pg/ml
Activity	<	7.8	pg/ml
Activity	<	7.8	pg/ml
Activity	<	7.8	pg/ml

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Androgen receptor

External ID: CHEMBL3864013

Protocol: N/A

Comment: Journal: ACS Med Chem Lett
Year: 2016
Volume: 7
Issue: 12
First Page: 1024
Last Page: 1027
DOI: 10.1021/acsmedchemlett.6b00180

Target ChEMBL ID: CHEMBL1871
ChEMBL Target Name: Androgen Receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Standard Type	Standard Units	Activity Comment
Inhibition	%	Active
Inhibition	%	Active
Inhibition	%	Active
Inhibition	%	Active
Inhibition	%	Active
Inhibition	%	Active
Inhibition	%	Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：PBMC

External ID: CHEMBL995725

Protocol: N/A

Comment: Journal: J. Nat. Prod.
Year: 2004
Volume: 67
Issue: 11
First Page: 1919
Last Page: 1924
DOI: 10.1021/np040006s

Target ChEMBL ID: CHEMBL613107
ChEMBL Target Name: PBMC
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	101.5	pg/ml
Activity	=	380	pg/ml
Activity	=	1245.2	pg/ml
Activity	=	59.8	pg/ml
Activity	=	2579.3	pg/ml
Activity	=	1477.6	pg/ml
Activity	<	7.8	pg/ml
Activity	=	783.6	pg/ml
Activity	=	705.7	pg/ml
Activity	=	793.2	pg/ml
Activity	<	7.8	pg/ml
Activity	=	473.4	pg/ml
Activity	=	28.1	pg/ml
Activity	=	32.2	pg/ml

84104-71-2 靶点实验数据