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831203-75-9 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Mus musculus
External ID: CHEMBL859215
Protocol: N/A
Comment: Journal: J Med Chem
Year: 2005
Volume: 48
Issue: 26
First Page: 8261
Last Page: 8269
DOI: 10.1021/jm050765n

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard UnitsActivity CommentData Validity Comment
2360.39Cmax=2360391.48nMstandard_value was converted from ug.mL-1 to nM using the parent compound MW
3740.36Cmax=3740364nMstandard_value was converted from ug.mL-1 to nM using the parent compound MW
8531.89Cmax=8531890.54nMstandard_value was converted from ug.mL-1 to nM using the parent compound MW
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Mycobacterium tuberculosis
External ID: CHEMBL860316
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 2005
Volume: 48
Issue: 26
First Page: 8261
Last Page: 8269
DOI: 10.1021/jm050765n

Target ChEMBL ID: CHEMBL360
ChEMBL Target Name: Mycobacterium tuberculosis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
MIC50=120ug.mL-1
MIC50=200ug.mL-1
MIC50=41ug.mL-1
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Mycobacterium tuberculosis
External ID: CHEMBL859213
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 2005
Volume: 48
Issue: 26
First Page: 8261
Last Page: 8269
DOI: 10.1021/jm050765n

Target ChEMBL ID: CHEMBL360
ChEMBL Target Name: Mycobacterium tuberculosis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
MIC50=41ug.mL-1
MIC50=41ug.mL-1
MIC50=14ug.mL-1
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Mycobacterium tuberculosis
External ID: CHEMBL860315
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 2005
Volume: 48
Issue: 26
First Page: 8261
Last Page: 8269
DOI: 10.1021/jm050765n

Target ChEMBL ID: CHEMBL360
ChEMBL Target Name: Mycobacterium tuberculosis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
MIC50=3.13ug.mL-1
MIC50=0.2ug.mL-1
MIC50=3.13ug.mL-1
MIC50=12.5ug.mL-1
MIC50=12.5ug.mL-1
MIC50=0.4ug.mL-1
MIC50=3.13ug.mL-1
MIC50=0.1ug.mL-1
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Mycobacterium tuberculosis
External ID: CHEMBL860322
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 2005
Volume: 48
Issue: 26
First Page: 8261
Last Page: 8269
DOI: 10.1021/jm050765n

Target ChEMBL ID: CHEMBL360
ChEMBL Target Name: Mycobacterium tuberculosis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard Value
Log10 cfu=3.88
Log10 cfu=7.53
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Mus musculus
External ID: CHEMBL859217
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 2005
Volume: 48
Issue: 26
First Page: 8261
Last Page: 8269
DOI: 10.1021/jm050765n

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
F>80%
F=21%
F=1%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Mus musculus
External ID: CHEMBL859216
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 2005
Volume: 48
Issue: 26
First Page: 8261
Last Page: 8269
DOI: 10.1021/jm050765n

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard UnitsActivity Comment
T1/2Not Determined
T1/2Not Determined
T1/2Not Determined
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Mus musculus
External ID: CHEMBL859214
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 2005
Volume: 48
Issue: 26
First Page: 8261
Last Page: 8269
DOI: 10.1021/jm050765n

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard UnitsActivity Comment
TmaxNot Determined
TmaxNot Determined
TmaxNot Determined