HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Micrococcus luteus

External ID: CHEMBL3631812

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2015
Volume: 25
Issue: 21
First Page: 4933
Last Page: 4936
DOI: 10.1016/j.bmcl.2015.04.099

Target ChEMBL ID: CHEMBL614421
ChEMBL Target Name: Micrococcus luteus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
IZ	=	0	mm
IZ	=	0	mm
IZ	=	0	mm
IZ	=	19	mm
IZ	=	0	mm

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Staphylococcus aureus

External ID: CHEMBL3631811

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2015
Volume: 25
Issue: 21
First Page: 4933
Last Page: 4936
DOI: 10.1016/j.bmcl.2015.04.099

Target ChEMBL ID: CHEMBL352
ChEMBL Target Name: Staphylococcus aureus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
IZ	=	18	mm
IZ	=	0	mm
IZ	=	0	mm
IZ	=	19	mm
IZ	=	0	mm

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Bacillus spizizenii

External ID: CHEMBL3631809

Protocol: N/A

Comment: Journal: Bioorg Med Chem Lett
Year: 2015
Volume: 25
Issue: 21
First Page: 4933
Last Page: 4936
DOI: 10.1016/j.bmcl.2015.04.099

Target ChEMBL ID: CHEMBL613907
ChEMBL Target Name: Bacillus spizizenii
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
IZ	=	0	mm
IZ	=	0	mm
IZ	=	19	mm
IZ	=	0	mm

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mycolicibacterium vaccae

External ID: CHEMBL3631814

Protocol: N/A

Comment: Journal: Bioorg Med Chem Lett
Year: 2015
Volume: 25
Issue: 21
First Page: 4933
Last Page: 4936
DOI: 10.1016/j.bmcl.2015.04.099

Target ChEMBL ID: CHEMBL613224
ChEMBL Target Name: Mycolicibacterium vaccae
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
IZ	=	20	mm
IZ	=	30	mm
IZ	=	15	mm
IZ	=	26	mm

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Pseudomonas aeruginosa

External ID: CHEMBL3631820

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2015
Volume: 25
Issue: 21
First Page: 4933
Last Page: 4936
DOI: 10.1016/j.bmcl.2015.04.099

Target ChEMBL ID: CHEMBL348
ChEMBL Target Name: Pseudomonas aeruginosa
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
IZ	=	19	mm
IZ	=	0	mm
IZ	=	14	mm
IZ	=	0	mm

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Pseudomonas aeruginosa

External ID: CHEMBL3631818

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2015
Volume: 25
Issue: 21
First Page: 4933
Last Page: 4936
DOI: 10.1016/j.bmcl.2015.04.099

Target ChEMBL ID: CHEMBL348
ChEMBL Target Name: Pseudomonas aeruginosa
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
IZ	=	23	mm
IZ	=	13	mm
IZ	=	0	mm
IZ	=	14	mm
IZ	=	14	mm

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Pseudomonas aeruginosa

External ID: CHEMBL3631817

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2015
Volume: 25
Issue: 21
First Page: 4933
Last Page: 4936
DOI: 10.1016/j.bmcl.2015.04.099

Target ChEMBL ID: CHEMBL348
ChEMBL Target Name: Pseudomonas aeruginosa
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
IZ	=	18	mm

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mycobacterium tuberculosis

External ID: CHEMBL3631808

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem. Lett.
Year: 2015
Volume: 25
Issue: 21
First Page: 4933
Last Page: 4936
DOI: 10.1016/j.bmcl.2015.04.099

Target ChEMBL ID: CHEMBL360
ChEMBL Target Name: Mycobacterium tuberculosis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
48.45	MIC	=	48450	nM
13.6	MIC	=	13600	nM
15.54	MIC	=	15540	nM
100	MIC	>	100000	nM
24.29	MIC	=	24290	nM
37.61	MIC	=	37610	nM
42.26	MIC	=	42260	nM
47.31	MIC	=	47310	nM
43.17	MIC	=	43170	nM
27.11	MIC	=	27110	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mycolicibacterium vaccae

External ID: CHEMBL3631823

Protocol: N/A

Comment: Journal: Bioorg Med Chem Lett
Year: 2015
Volume: 25
Issue: 21
First Page: 4933
Last Page: 4936
DOI: 10.1016/j.bmcl.2015.04.099

Target ChEMBL ID: CHEMBL613224
ChEMBL Target Name: Mycolicibacterium vaccae
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
DIZ				Not Determined
IZ	=	6.25	mm
DIZ				Not Determined
DIZ				Not Determined
IZ	=	12.5	mm

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mycobacterium tuberculosis

External ID: CHEMBL3631807

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem. Lett.
Year: 2015
Volume: 25
Issue: 21
First Page: 4933
Last Page: 4936
DOI: 10.1016/j.bmcl.2015.04.099

Target ChEMBL ID: CHEMBL360
ChEMBL Target Name: Mycobacterium tuberculosis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
100	MIC	>	100000	nM
90.42	MIC	=	90420	nM
47.31	MIC	=	47310	nM
100	MIC	>	100000	nM
50	MIC	>	50000	nM
100	MIC	>	100000	nM
100	MIC	>	100000	nM
100	MIC	>	100000	nM
100	MIC	>	100000	nM
86.59	MIC	=	86590	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Escherichia coli

External ID: CHEMBL3631822

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2015
Volume: 25
Issue: 21
First Page: 4933
Last Page: 4936
DOI: 10.1016/j.bmcl.2015.04.099

Target ChEMBL ID: CHEMBL354
ChEMBL Target Name: Escherichia coli
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
IZ	=	21	mm
IZ	=	0	mm
IZ	=	16	mm
IZ	=	0	mm
IZ	=	0	mm

82475-72-7 靶点实验数据