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80357-35-3 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Rattus norvegicus
External ID: CHEMBL872405
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 1982
Volume: 25
Issue: 2
First Page: 131
Last Page: 136
DOI: 10.1021/jm00344a008

Target ChEMBL ID: CHEMBL376
ChEMBL Target Name: Rattus norvegicus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
ED50=200mg.kg-1
ED50=2.8mg.kg-1
ED50=84.8mg.kg-1
ED50=200mg.kg-1
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Rattus norvegicus
External ID: CHEMBL781233
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 1982
Volume: 25
Issue: 2
First Page: 131
Last Page: 136
DOI: 10.1021/jm00344a008

Target ChEMBL ID: CHEMBL376
ChEMBL Target Name: Rattus norvegicus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
ED50=4.55mg.kg-1
ED50=0.54mg.kg-1
ED50=80mg.kg-1
ED50=28mg.kg-1
ED50=200mg.kg-1
ED50>200mg.kg-1
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Mus musculus
External ID: CHEMBL727608
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 1982
Volume: 25
Issue: 2
First Page: 131
Last Page: 136
DOI: 10.1021/jm00344a008

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
LD50=422mg.kg-1
LD50=56mg.kg-1
LD50=562mg.kg-1
LD50=562mg.kg-1
LD50=562mg.kg-1
LD50=562mg.kg-1
LD50=300mg.kg-1
LD50=562mg.kg-1
LD50=562mg.kg-1
LD50=562mg.kg-1
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Rattus norvegicus
External ID: CHEMBL789097
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 1982
Volume: 25
Issue: 2
First Page: 131
Last Page: 136
DOI: 10.1021/jm00344a008

Target ChEMBL ID: CHEMBL376
ChEMBL Target Name: Rattus norvegicus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
Reduction=58%
Reduction=62%
Reduction=17%
Reduction=49%
Reduction=0%
Reduction=23%
Reduction=6%
Reduction=26%
Reduction=25%
Reduction=33%
Reduction=2%
Reduction=8%
Reduction=0%