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80258-99-7 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Protein polybromo-1
External ID: CHEMBL5112650
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 20.0
First Page: 13714
Last Page: 13735
DOI: 10.1021/acs.jmedchem.2c00864

Target ChEMBL ID: CHEMBL1795184
ChEMBL Target Name: Protein polybromo-1
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
0.2IC50=200nM
0.26IC50=260nM
1.1IC50=1100nM
119IC50=119000nM
26IC50=26000nM
250IC50>250000nM
0.16IC50=160nM
5.6IC50=5600nM
89.9IC50=89900nM
0.87IC50=870nM
6.3IC50=6300nM