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79418-74-9 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Catechol O-methyltransferase
External ID: CHEMBL661919
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1982
Volume: 25
Issue: 3
First Page: 258
Last Page: 263
DOI: 10.1021/jm00345a012

Target ChEMBL ID: CHEMBL2372
ChEMBL Target Name: Catechol O-methyltransferase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
9.98Kis=9.98uM
0.7Kis=0.7uM
111.3Kis=111.3uM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Catechol O-methyltransferase
External ID: CHEMBL856129
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 1982
Volume: 25
Issue: 3
First Page: 258
Last Page: 263
DOI: 10.1021/jm00345a012

Target ChEMBL ID: CHEMBL2372
ChEMBL Target Name: Catechol O-methyltransferase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned
Standard TypeStandard UnitsActivity Comment
Inhibition%Noncompetitive kinetics