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79185-75-4 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Cyclin-dependent kinase 2
External ID: CHEMBL1067148
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem. Lett.
Year: 2010
Volume: 20
Issue: 4
First Page: 1384
Last Page: 1387
DOI: 10.1016/j.bmcl.2010.01.007

Target ChEMBL ID: CHEMBL301
ChEMBL Target Name: Cyclin-dependent kinase 2
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
50IC50>50000nM
50IC50>50000nM
50IC50>50000nM
50IC50>50000nM
20IC50>20000nM
1.2IC50=1200nM
13.4IC50=13400nM
18IC50=18000nM
30IC50>30000nM
2.9IC50=2900nM
0.035IC50=35nM
30IC50>30000nM
2.15IC50=2150nM
35IC50>35000nM
0.02IC50=20nM
20IC50>20000nM
15IC50=15000nM
20IC50>20000nM
50IC50>50000nM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:Shanghai Institute of Organic Chemistry 靶标:N/A
External ID: PDBbind-Ki for protein-ligand complexes
Protocol:
Comment:
PDBbind Data LinkAffinity_QuilifierKiPubMedProtein TargetProtein NameMMDBPDB
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1mto=0.11123900231MTO_A,1MTO_B6-phosphofructokinase214801MTO
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1mu6=0.0042125703691MU6_Bthrombin alpha267361MU6
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1mue=0.0023126572811MUE_Bthrombin alpha267381MUE
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1mx1>100127258621MX1_Acarboxylesterase i226511MX1
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1mxo=0.0011MXO_Abeta-lactamase220611MXO
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1my8=0.0351MY8_Abeta-lactamase220641MY8
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1n1v=140125074791N1V_Aneuraminidase (sialidase)218101N1V
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1n2v=83126460241N2V_Aqueuine tRNA-ribosyltransferase226611N2V
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1n3i=0.0013127556071N3I_A,1N3I_Bpurine nucleoside phosphorylase246461N3I
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1n46=3.0E-5125659331N46_Athyroid hormone receptor beta-1226621N46
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1n4h=0.28129585911N4H_Anuclear receptor ror-beta246471N4H
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1n5r=2.2125059791N5R_Aacetylcholinesterase218341N5R
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1n7i=0.26146958181N7I_Aphenylethanolamine n-methyltransferase255971N7I
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1nc1=0.75124962431NC1_A,1NC1_Bmta/sah nucleosidase252501NC1
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1nc3=10124962431NC3_A,1NC3_Bmta/sah nucleosidase223901NC3
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1nde=0.015124590171NDE_Aestrogen receptor beta215441NDE
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1ndz=0.0077147090461NDZ_Aadenosine deaminase256131NDZ
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1nhv=2.2125094361NHV_Arna-dependent rna polymerase224031NHV
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1nny=0.022126702291NNY_Atyrosine phosphatase 1b226961NNY
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1noj=70086525101NOJ_Aglycogen phosphorylase569921NOJ
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Cyclin-dependent kinase 2
External ID: CHEMBL1067154
Protocol: N/A
Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2010
Volume: 20
Issue: 4
First Page: 1384
Last Page: 1387
DOI: 10.1016/j.bmcl.2010.01.007

Target ChEMBL ID: CHEMBL301
ChEMBL Target Name: Cyclin-dependent kinase 2
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned
Standard TypeActivity Comment
ActivityNot Active
ActivityNot Active
ActivityNot Active
ActivityNot Active
ActivityNot Active
ActivityNot Active
ActivityNot Active
ActivityNot Active
ActivityNot Active
ActivityNot Active
ActivityNot Active
ActivityNot Active
ActivityNot Active