HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL813698

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1990
Volume: 33
Issue: 1
First Page: 112
Last Page: 121
DOI: 10.1021/jm00163a019

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
13.6	IC50	=	13600	nM
0.16	IC50	=	160	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL846026

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1990
Volume: 33
Issue: 1
First Page: 112
Last Page: 121
DOI: 10.1021/jm00163a019

Standard Type	Standard Relation	Standard Value
Ratio	~	39
Ratio	=	25
Ratio	>	1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL634147

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1990
Volume: 33
Issue: 1
First Page: 112
Last Page: 121
DOI: 10.1021/jm00163a019

Standard Type	Standard Relation	Standard Value	Standard Units
T1/2	=	7.2	hr
T1/2	=	12.6	hr
T1/2	=	0.4	hr
T1/2	=	1.5	hr
T1/2	>	100	hr
T1/2	=	2.5	hr
T1/2	=	6.3	hr
T1/2	=	3.5	hr
T1/2	=	5.9	hr
T1/2	=	13.7	hr
T1/2	=	0.134	hr

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL846025

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1990
Volume: 33
Issue: 1
First Page: 112
Last Page: 121
DOI: 10.1021/jm00163a019

Standard Type	Standard Relation	Standard Value
Ratio	~	28
Ratio	=	19
Ratio	>	1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL850884

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1990
Volume: 33
Issue: 1
First Page: 112
Last Page: 121
DOI: 10.1021/jm00163a019

Standard Type	Standard Relation	Standard Value
Ratio	=	0.94
Ratio	=	0.98
Ratio	=	1.5
Ratio	=	0.66

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL813696

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1990
Volume: 33
Issue: 1
First Page: 112
Last Page: 121
DOI: 10.1021/jm00163a019

Standard Type	Standard Relation	Standard Value	Standard Units
CT10	=	3.1	uM hr-1
CT10	=	1	uM hr-1
CT10	=	0.23	uM hr-1
CT10	=	2.9	uM hr-1
CT10	=	1120	uM hr-1
CT10	=	3	uM hr-1
CT10	<	0.1	uM hr-1
CT10	=	0.043	uM hr-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL846024

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1990
Volume: 33
Issue: 1
First Page: 112
Last Page: 121
DOI: 10.1021/jm00163a019

Standard Type	Standard Relation	Standard Value
Ratio	=	30
Ratio	=	42
Ratio	=	46
Ratio	=	3.5
Ratio	=	52
Ratio	=	42
Ratio	=	50
Ratio	=	41
Ratio	>	20
Ratio	>	1
Ratio	=	8
Ratio	>	1
Ratio	=	42
Ratio	=	25

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL623828

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1990
Volume: 33
Issue: 1
First Page: 112
Last Page: 121
DOI: 10.1021/jm00163a019

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
2.9	IC50	=	2900	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL814371

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1990
Volume: 33
Issue: 1
First Page: 112
Last Page: 121
DOI: 10.1021/jm00163a019

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
0.21	IC50	=	210	nM
42	IC50	=	42000	nM
0.33	IC50	=	330	nM
0.57	IC50	=	570	nM
0.15	IC50	=	150	nM
1.5	IC50	=	1500	nM
0.04	IC50	=	40	nM
6.8	IC50	=	6800	nM
13.6	IC50	=	13600	nM
21.5	IC50	=	21500	nM
0.16	IC50	=	160	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL813700

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1990
Volume: 33
Issue: 1
First Page: 112
Last Page: 121
DOI: 10.1021/jm00163a019

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
0.4	IC50	=	400	nM
174	IC50	=	174000	nM	Outside typical range
1.2	IC50	=	1200	nM
2.7	IC50	=	2700	nM
1.2	IC50	=	1200	nM
7.6	IC50	=	7600	nM
0.1	IC50	<	100	nM
76	IC50	=	76000	nM
96	IC50	=	96000	nM
15.8	IC50	=	15800	nM
0.38	IC50	=	380	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL848367

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1990
Volume: 33
Issue: 1
First Page: 112
Last Page: 121
DOI: 10.1021/jm00163a019

Standard Type	Standard Relation	Standard Value
CT10	=	1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL873888

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1990
Volume: 33
Issue: 1
First Page: 112
Last Page: 121
DOI: 10.1021/jm00163a019

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
1	IC50	=	1000	nM

779-28-2 靶点实验数据